Filtering failure: the impact of automated indexing in Medline on retrieval of human studies for knowledge synthesis

Objective: Use of the search filter ‘exp animals/ not humans.sh’ is a well-established method in evidence synthesis to exclude non-human studies. However, the shift to automated indexing of Medline records has raised concerns about the use of subject-heading-based search techniques. We sought to de...

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Main Authors: Nicole Askin, Tyler Ostapyk, Carla Epp
Format: Article
Language:English
Published: University Library System, University of Pittsburgh 2025-01-01
Series:Journal of the Medical Library Association
Subjects:
Online Access:http://jmla.pitt.edu/ojs/jmla/article/view/1972
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author Nicole Askin
Tyler Ostapyk
Carla Epp
author_facet Nicole Askin
Tyler Ostapyk
Carla Epp
author_sort Nicole Askin
collection DOAJ
description Objective: Use of the search filter ‘exp animals/ not humans.sh’ is a well-established method in evidence synthesis to exclude non-human studies. However, the shift to automated indexing of Medline records has raised concerns about the use of subject-heading-based search techniques. We sought to determine how often this string inappropriately excludes human studies among automated as compared to manually indexed records in Ovid Medline. Methods: We searched Ovid Medline for studies published in 2021 and 2022 using the Cochrane Highly Sensitive Search Strategy for randomized trials. We identified all results excluded by the non-human-studies filter. Records were divided into sets based on indexing method: automated, curated, or manual. Each set was screened to identify human studies. Results: Human studies were incorrectly excluded in all three conditions, but automated indexing inappropriately excluded human studies at nearly double the rate as manual indexing. In looking specifically at human clinical randomized controlled trials (RCTs), the rate of inappropriate exclusion of automated-indexing records was seven times that of manually-indexed records. Conclusions: Given our findings, searchers are advised to carefully review the effect of the ‘exp animals/ not humans.sh’ search filter on their search results, pending improvements to the automated indexing process.
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spelling doaj-art-abc7398ad705442eb96b8f84ef3fda1e2025-01-14T23:39:30ZengUniversity Library System, University of PittsburghJournal of the Medical Library Association1536-50501558-94392025-01-01113110.5195/jmla.2025.1972Filtering failure: the impact of automated indexing in Medline on retrieval of human studies for knowledge synthesisNicole Askin0Tyler OstapykCarla EppUniversity of Manitoba Objective: Use of the search filter ‘exp animals/ not humans.sh’ is a well-established method in evidence synthesis to exclude non-human studies. However, the shift to automated indexing of Medline records has raised concerns about the use of subject-heading-based search techniques. We sought to determine how often this string inappropriately excludes human studies among automated as compared to manually indexed records in Ovid Medline. Methods: We searched Ovid Medline for studies published in 2021 and 2022 using the Cochrane Highly Sensitive Search Strategy for randomized trials. We identified all results excluded by the non-human-studies filter. Records were divided into sets based on indexing method: automated, curated, or manual. Each set was screened to identify human studies. Results: Human studies were incorrectly excluded in all three conditions, but automated indexing inappropriately excluded human studies at nearly double the rate as manual indexing. In looking specifically at human clinical randomized controlled trials (RCTs), the rate of inappropriate exclusion of automated-indexing records was seven times that of manually-indexed records. Conclusions: Given our findings, searchers are advised to carefully review the effect of the ‘exp animals/ not humans.sh’ search filter on their search results, pending improvements to the automated indexing process. http://jmla.pitt.edu/ojs/jmla/article/view/1972Evidence SynthesisAbstract and IndexingMedical Subject Headings (MeSH)Automated indexing
spellingShingle Nicole Askin
Tyler Ostapyk
Carla Epp
Filtering failure: the impact of automated indexing in Medline on retrieval of human studies for knowledge synthesis
Journal of the Medical Library Association
Evidence Synthesis
Abstract and Indexing
Medical Subject Headings (MeSH)
Automated indexing
title Filtering failure: the impact of automated indexing in Medline on retrieval of human studies for knowledge synthesis
title_full Filtering failure: the impact of automated indexing in Medline on retrieval of human studies for knowledge synthesis
title_fullStr Filtering failure: the impact of automated indexing in Medline on retrieval of human studies for knowledge synthesis
title_full_unstemmed Filtering failure: the impact of automated indexing in Medline on retrieval of human studies for knowledge synthesis
title_short Filtering failure: the impact of automated indexing in Medline on retrieval of human studies for knowledge synthesis
title_sort filtering failure the impact of automated indexing in medline on retrieval of human studies for knowledge synthesis
topic Evidence Synthesis
Abstract and Indexing
Medical Subject Headings (MeSH)
Automated indexing
url http://jmla.pitt.edu/ojs/jmla/article/view/1972
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