A longitudinal study on sleep quality of patients with stage 4 chronic kidney disease,subject to hemodialysis and peritoneal dialysis

Objective A longitudinal research was conducted in our center to observe the dynamic change of sleep quality of patients with stage 4 chronic kidney disease(CKD),subject to hemodialysis and continuous ambulatory peritoneal dialysis(CAPD) and to investigate the associated factors.Methods Patients wit...

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Main Authors: LUO Min-hong, YUAN Li-ping, CHEN Qiu-lian, ZHU Lang-jing, ZENG Hai-ou, CHEN Zhen-wei, WU Qiang, YANG Tie-cheng
Format: Article
Language:zho
Published: Editorial Department of Journal of Clinical Nephrology 2015-01-01
Series:Linchuang shenzangbing zazhi
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Online Access:http://www.lcszb.com/thesisDetails?columnId=57920087&Fpath=home&index=0
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author LUO Min-hong
YUAN Li-ping
CHEN Qiu-lian
ZHU Lang-jing
ZENG Hai-ou
CHEN Zhen-wei
WU Qiang
YANG Tie-cheng
author_facet LUO Min-hong
YUAN Li-ping
CHEN Qiu-lian
ZHU Lang-jing
ZENG Hai-ou
CHEN Zhen-wei
WU Qiang
YANG Tie-cheng
author_sort LUO Min-hong
collection DOAJ
description Objective A longitudinal research was conducted in our center to observe the dynamic change of sleep quality of patients with stage 4 chronic kidney disease(CKD),subject to hemodialysis and continuous ambulatory peritoneal dialysis(CAPD) and to investigate the associated factors.Methods Patients with CKD stage 4(n = 43),hemodialysis(n = 41) and CAPD(n = 44) were included and followed up for 1 year.Pittsburgh Sleep Quality Index(PSQI) and laboratory parameters were evaluated every 6 months.The univariate and multivariate Logistic regression analysis was used to analyze the associated factors.Results There was no significant difference in age,sex,socio-economic factors,smoking,BMI,Charlson comorbidity index and primary renal disease among the three groups(P>0.05).At the baseline and sixth month,the PSQI scores in hemodialysis and CAPD groups were significantly higher than those in CKD stage 4 group(P<0.05).At the twelfth month,there was no significant difference in PSQI scores among the three groups(P<0.05).As compared with the baseline values,the PSQI scores among the three groups at the sixth month were all significantly increased(P<0.05).As compared with the values at sixth month,the PSQI scores in CKD stage 4 group at the twelfth month were significantly increased(P<0.05),and those in hemodialysis and CAPD groups had no significant change.With the dynamic changes of the total PSQI score,hemoglobin,calcium and phosphorus product,intact parathyroid hormone and high-sensitivity C-reactive protein also changed in the three groups.Age(OR=1.83,P=0.01),hemoglobin(OR=1.46,P=0.01),calcium and phosphorus product(OR=1.25,P=0.02),intact parathyroid hormone(OR=1.17,P=0.03),and high sensitivity C-reactive protein(OR=1.32,P=0.04)were significantly related to poor sleep.Conclusions The sleep quality of patients with CKD stage 4,subject to hemodialysis and CAPD progressively deteriorated.Older age,anemia,the disorders of calcium phosphate metabolism and the microinflammatory status are the independent risk factors of poor sleep quality.
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spelling doaj-art-abc62aad84f44ab78b7ae616cbb9edfe2025-08-20T03:52:51ZzhoEditorial Department of Journal of Clinical NephrologyLinchuang shenzangbing zazhi1671-23902015-01-0135936357920087A longitudinal study on sleep quality of patients with stage 4 chronic kidney disease,subject to hemodialysis and peritoneal dialysisLUO Min-hongYUAN Li-pingCHEN Qiu-lianZHU Lang-jingZENG Hai-ouCHEN Zhen-weiWU QiangYANG Tie-chengObjective A longitudinal research was conducted in our center to observe the dynamic change of sleep quality of patients with stage 4 chronic kidney disease(CKD),subject to hemodialysis and continuous ambulatory peritoneal dialysis(CAPD) and to investigate the associated factors.Methods Patients with CKD stage 4(n = 43),hemodialysis(n = 41) and CAPD(n = 44) were included and followed up for 1 year.Pittsburgh Sleep Quality Index(PSQI) and laboratory parameters were evaluated every 6 months.The univariate and multivariate Logistic regression analysis was used to analyze the associated factors.Results There was no significant difference in age,sex,socio-economic factors,smoking,BMI,Charlson comorbidity index and primary renal disease among the three groups(P>0.05).At the baseline and sixth month,the PSQI scores in hemodialysis and CAPD groups were significantly higher than those in CKD stage 4 group(P<0.05).At the twelfth month,there was no significant difference in PSQI scores among the three groups(P<0.05).As compared with the baseline values,the PSQI scores among the three groups at the sixth month were all significantly increased(P<0.05).As compared with the values at sixth month,the PSQI scores in CKD stage 4 group at the twelfth month were significantly increased(P<0.05),and those in hemodialysis and CAPD groups had no significant change.With the dynamic changes of the total PSQI score,hemoglobin,calcium and phosphorus product,intact parathyroid hormone and high-sensitivity C-reactive protein also changed in the three groups.Age(OR=1.83,P=0.01),hemoglobin(OR=1.46,P=0.01),calcium and phosphorus product(OR=1.25,P=0.02),intact parathyroid hormone(OR=1.17,P=0.03),and high sensitivity C-reactive protein(OR=1.32,P=0.04)were significantly related to poor sleep.Conclusions The sleep quality of patients with CKD stage 4,subject to hemodialysis and CAPD progressively deteriorated.Older age,anemia,the disorders of calcium phosphate metabolism and the microinflammatory status are the independent risk factors of poor sleep quality.http://www.lcszb.com/thesisDetails?columnId=57920087&Fpath=home&index=0Chronic kidney diseaseHemodialysisPeritoneal dialysisSleep
spellingShingle LUO Min-hong
YUAN Li-ping
CHEN Qiu-lian
ZHU Lang-jing
ZENG Hai-ou
CHEN Zhen-wei
WU Qiang
YANG Tie-cheng
A longitudinal study on sleep quality of patients with stage 4 chronic kidney disease,subject to hemodialysis and peritoneal dialysis
Linchuang shenzangbing zazhi
Chronic kidney disease
Hemodialysis
Peritoneal dialysis
Sleep
title A longitudinal study on sleep quality of patients with stage 4 chronic kidney disease,subject to hemodialysis and peritoneal dialysis
title_full A longitudinal study on sleep quality of patients with stage 4 chronic kidney disease,subject to hemodialysis and peritoneal dialysis
title_fullStr A longitudinal study on sleep quality of patients with stage 4 chronic kidney disease,subject to hemodialysis and peritoneal dialysis
title_full_unstemmed A longitudinal study on sleep quality of patients with stage 4 chronic kidney disease,subject to hemodialysis and peritoneal dialysis
title_short A longitudinal study on sleep quality of patients with stage 4 chronic kidney disease,subject to hemodialysis and peritoneal dialysis
title_sort longitudinal study on sleep quality of patients with stage 4 chronic kidney disease subject to hemodialysis and peritoneal dialysis
topic Chronic kidney disease
Hemodialysis
Peritoneal dialysis
Sleep
url http://www.lcszb.com/thesisDetails?columnId=57920087&Fpath=home&index=0
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