Analysis on Soy-Yamgurt Potential as Antidiabetic in Streptozotocin-Nicotinamide Induced Rats
This study was conducted to determine the potential of soy-yamgurt probiotics drink from the mixture of yam and soy extract with a ratio of 1: 1 in reducing the fasting blood glucose level of rats induced by streptozotocin-nicotinamide. Based on the analysis of chemical and phytochemical characteri...
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TALENTA
2018-03-01
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| Series: | Indonesian Journal of Agricultural Research |
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| Online Access: | https://dev-talenta.usu.ac.id/InJAR/article/view/174 |
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| author | Jessica Kwanariesta Herla Rusmarilin Ismed Suhaidi |
| author_facet | Jessica Kwanariesta Herla Rusmarilin Ismed Suhaidi |
| author_sort | Jessica Kwanariesta |
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This study was conducted to determine the potential of soy-yamgurt probiotics drink from the mixture of yam and soy extract with a ratio of 1: 1 in reducing the fasting blood glucose level of rats induced by streptozotocin-nicotinamide. Based on the analysis of chemical and phytochemical characteristics of soy-yamgurt, it was found that it has water content (80.97%), total solids (18.85%), protein content (11.95%), total lactic acid (1.03%), viscosity (20.56 Pa.s), lactic acid bacteria (10.22 log CFU/g), fiber content (0.98%), IC50 value (44.99 μg/ml), total phenol (711.90 μgGAE/g) and total flavonoids (1345.73 μgQE/g). The in vivo test used thirty 10-16 week old male Wistar rats with an average weight of 160-200 g divided into 5 groups: P1 (control), P2 (streptozotocin-nicotinamide), P3 (glibenclamide of 0.45 mg/kg body weight), P4 (3 ml of soy-yamgurt) and P5 (3.5 ml of soy-yamgurt).The results showed that the soy-yamgurt at the doses of 3 ml/160 g body weight and 3.5 ml/160 g body weight for 4 weeks in streptozotocin-nicotinamide-induced rats had significantly (P<0.01) lowered blood glucose levels and increased their weight.
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| format | Article |
| id | doaj-art-aba36c5349cd411c8d41a66cbf5cb51d |
| institution | Kabale University |
| issn | 2622-7681 2615-5842 |
| language | English |
| publishDate | 2018-03-01 |
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| series | Indonesian Journal of Agricultural Research |
| spelling | doaj-art-aba36c5349cd411c8d41a66cbf5cb51d2025-01-04T11:23:59ZengTALENTAIndonesian Journal of Agricultural Research2622-76812615-58422018-03-0111Analysis on Soy-Yamgurt Potential as Antidiabetic in Streptozotocin-Nicotinamide Induced RatsJessica Kwanariesta0Herla Rusmarilin1Ismed Suhaidi2Department of Food Science and Technology, Faculty of Agriculture, Universitas Sumatera UtaraDepartment of Food Science and Technology, Faculty of Agriculture, Universitas Sumatera UtaraDepartment of Food Science and Technology, Faculty of Agriculture, Universitas Sumatera Utara This study was conducted to determine the potential of soy-yamgurt probiotics drink from the mixture of yam and soy extract with a ratio of 1: 1 in reducing the fasting blood glucose level of rats induced by streptozotocin-nicotinamide. Based on the analysis of chemical and phytochemical characteristics of soy-yamgurt, it was found that it has water content (80.97%), total solids (18.85%), protein content (11.95%), total lactic acid (1.03%), viscosity (20.56 Pa.s), lactic acid bacteria (10.22 log CFU/g), fiber content (0.98%), IC50 value (44.99 μg/ml), total phenol (711.90 μgGAE/g) and total flavonoids (1345.73 μgQE/g). The in vivo test used thirty 10-16 week old male Wistar rats with an average weight of 160-200 g divided into 5 groups: P1 (control), P2 (streptozotocin-nicotinamide), P3 (glibenclamide of 0.45 mg/kg body weight), P4 (3 ml of soy-yamgurt) and P5 (3.5 ml of soy-yamgurt).The results showed that the soy-yamgurt at the doses of 3 ml/160 g body weight and 3.5 ml/160 g body weight for 4 weeks in streptozotocin-nicotinamide-induced rats had significantly (P<0.01) lowered blood glucose levels and increased their weight. https://dev-talenta.usu.ac.id/InJAR/article/view/174antioxidant activity, diabetes mellitus, soy milk, soy-yamgurt, streptozotocin-nicotinamide |
| spellingShingle | Jessica Kwanariesta Herla Rusmarilin Ismed Suhaidi Analysis on Soy-Yamgurt Potential as Antidiabetic in Streptozotocin-Nicotinamide Induced Rats Indonesian Journal of Agricultural Research antioxidant activity, diabetes mellitus, soy milk, soy-yamgurt, streptozotocin-nicotinamide |
| title | Analysis on Soy-Yamgurt Potential as Antidiabetic in Streptozotocin-Nicotinamide Induced Rats |
| title_full | Analysis on Soy-Yamgurt Potential as Antidiabetic in Streptozotocin-Nicotinamide Induced Rats |
| title_fullStr | Analysis on Soy-Yamgurt Potential as Antidiabetic in Streptozotocin-Nicotinamide Induced Rats |
| title_full_unstemmed | Analysis on Soy-Yamgurt Potential as Antidiabetic in Streptozotocin-Nicotinamide Induced Rats |
| title_short | Analysis on Soy-Yamgurt Potential as Antidiabetic in Streptozotocin-Nicotinamide Induced Rats |
| title_sort | analysis on soy yamgurt potential as antidiabetic in streptozotocin nicotinamide induced rats |
| topic | antioxidant activity, diabetes mellitus, soy milk, soy-yamgurt, streptozotocin-nicotinamide |
| url | https://dev-talenta.usu.ac.id/InJAR/article/view/174 |
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