The mechanism of Shancigu and its monomer in the development of colorectal cancer based on network pharmacology

The mechanism of Shancigu and its monomer in the development of colorectal cancer based on network pharmacology

Abstract Shancigu has traditionally been used for clearing heat, detoxification, resolving phlegm, and dissipating masses. However, its potential mechanisms in colorectal cancer (CRC) remain unclear. This study aimed to explore the molecular mechanisms of Shancigu and its active compound in CRC. The...

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Bibliographic Details
Main Authors: Guiying Li, Xiuqiong Zhu, Ruixia Zhao, Xi Zhang, Cuimei Huang, Miaomiao Shu, Liangying Liu, Jie Yuan
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Network pharmacology
Shancigu
Stigmasterol
ITGB1
JUN
Colorectal cancer
Online Access:https://doi.org/10.1038/s41598-025-04795-7
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https://doi.org/10.1038/s41598-025-04795-7

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