The rate of liver impairment, character of bacteremia and serum bactericidal activity in patients with cirrhosis

Dependence of prevalence and severity of bacteremia on the rate of liver impairment, serum bactericidal activity (SBA), and serum concentrations of C-reactive protein (CRP) and granulocyte colony-stimulating factor (G-CSF) in 80 hospitalized patients with liver cirrhosis (LC) have been studied. It w...

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Main Authors: Krutikov S.N., Krivorutchenko Yu.L., Postnikova O.N., Krutikova M.S., Logadir T.A.
Format: Article
Language:English
Published: Dnipro State Medical University 2014-06-01
Series:Medičnì Perspektivi
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Online Access:http://medpers.dsma.dp.ua/issues/2014/N2/39-45.pdf
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author Krutikov S.N.
Krivorutchenko Yu.L.
Postnikova O.N.
Krutikova M.S.
Logadir T.A.
author_facet Krutikov S.N.
Krivorutchenko Yu.L.
Postnikova O.N.
Krutikova M.S.
Logadir T.A.
author_sort Krutikov S.N.
collection DOAJ
description Dependence of prevalence and severity of bacteremia on the rate of liver impairment, serum bactericidal activity (SBA), and serum concentrations of C-reactive protein (CRP) and granulocyte colony-stimulating factor (G-CSF) in 80 hospitalized patients with liver cirrhosis (LC) have been studied. It was shown that risk factors associated with the development of bacteremia are high by Child-Pugh score and low SBA, CRP and G-CSF levels. Patients with LC, class A had the highest SBA, CRP and G-CSF levels. Still 14,3% of them developed less severe bacteremia associated with one type of microorganisms isolated from blood. Patients with LC, class B had intermediate SBA, CRP and G-CSF levels. They developed severe bacteremia in 52,6% of cases and less severe bacteremia – in 21,1% of cases. Patients with LC, class C had low SBA, CRP and G-CSF levels. They developed severe bacteremia in 62,5% of cases and less severe bacteremia – in 25% of cases.
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series Medičnì Perspektivi
spelling doaj-art-ab64eaef00d349b9aa6cfb5fcf5864c72024-12-02T09:52:35ZengDnipro State Medical UniversityMedičnì Perspektivi2307-04042307-04042014-06-011923945The rate of liver impairment, character of bacteremia and serum bactericidal activity in patients with cirrhosisKrutikov S.N.0Krivorutchenko Yu.L.1Postnikova O.N.2Krutikova M.S.3Logadir T.A. 4SI «Crimean State Medical University named after S.I. Georgievsky»SI «Crimean State Medical University named after S.I. Georgievsky»SI «Crimean State Medical University named after S.I. Georgievsky»SI «Crimean State Medical University named after S.I. Georgievsky»SI «Crimean State Medical University named after S.I. Georgievsky»Dependence of prevalence and severity of bacteremia on the rate of liver impairment, serum bactericidal activity (SBA), and serum concentrations of C-reactive protein (CRP) and granulocyte colony-stimulating factor (G-CSF) in 80 hospitalized patients with liver cirrhosis (LC) have been studied. It was shown that risk factors associated with the development of bacteremia are high by Child-Pugh score and low SBA, CRP and G-CSF levels. Patients with LC, class A had the highest SBA, CRP and G-CSF levels. Still 14,3% of them developed less severe bacteremia associated with one type of microorganisms isolated from blood. Patients with LC, class B had intermediate SBA, CRP and G-CSF levels. They developed severe bacteremia in 52,6% of cases and less severe bacteremia – in 21,1% of cases. Patients with LC, class C had low SBA, CRP and G-CSF levels. They developed severe bacteremia in 62,5% of cases and less severe bacteremia – in 25% of cases.http://medpers.dsma.dp.ua/issues/2014/N2/39-45.pdfliver cirrhosis; liver impairment; bacteremia; serum bactericidal activityliver cirrhosisliver impairmentbacteremiaserum bactericidal activity
spellingShingle Krutikov S.N.
Krivorutchenko Yu.L.
Postnikova O.N.
Krutikova M.S.
Logadir T.A.
The rate of liver impairment, character of bacteremia and serum bactericidal activity in patients with cirrhosis
Medičnì Perspektivi
liver cirrhosis; liver impairment; bacteremia; serum bactericidal activity
liver cirrhosis
liver impairment
bacteremia
serum bactericidal activity
title The rate of liver impairment, character of bacteremia and serum bactericidal activity in patients with cirrhosis
title_full The rate of liver impairment, character of bacteremia and serum bactericidal activity in patients with cirrhosis
title_fullStr The rate of liver impairment, character of bacteremia and serum bactericidal activity in patients with cirrhosis
title_full_unstemmed The rate of liver impairment, character of bacteremia and serum bactericidal activity in patients with cirrhosis
title_short The rate of liver impairment, character of bacteremia and serum bactericidal activity in patients with cirrhosis
title_sort rate of liver impairment character of bacteremia and serum bactericidal activity in patients with cirrhosis
topic liver cirrhosis; liver impairment; bacteremia; serum bactericidal activity
liver cirrhosis
liver impairment
bacteremia
serum bactericidal activity
url http://medpers.dsma.dp.ua/issues/2014/N2/39-45.pdf
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