Benzbromarone Analog SAR: Potent hURAT1 (SLC22A12) Inhibitors and Drug Transporter Interaction Studies

Benzbromarone Analog SAR: Potent hURAT1 (SLC22A12) Inhibitors and Drug Transporter Interaction Studies

Promsuk Jutabha,1,2 Vijay Kumar,3 Naohiko Anzai,2,4 Peter J Rice,5,6 Janet W Lightner,6 Hitoshi Endou,7 Michael F Wempe3,8,9 1Chakri Naruebodindra Medical Institute, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Samut Prakarn, 10540, Thailand; 2Department of Pharmacology and Toxicolo...

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Bibliographic Details
Main Authors: Jutabha P, Kumar V, Anzai N, Rice PJ, Lightner JW, Endou H, Wempe MF
Format: Article
Language:English
Published: Dove Medical Press 2025-02-01
Series:Drug Design, Development and Therapy
Subjects:
oocyte transporter system
eadie-hofstee plot
rat pharmacokinetics
organic anion drug transporters
Online Access:https://www.dovepress.com/benzbromarone-analog-sar-potent-hurat1-slc22a12-inhibitors-and-drug-tr-peer-reviewed-fulltext-article-DDDT
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