An effective approach for water pollution remediation and structural-optical analysis of gamma-irradiated flufenamic acid

The escalating presence of pharmaceutical pollutants in aquatic ecosystems poses a significant environmental challenge, necessitating the exploration of innovative remediation strategies. Flufenamic acid, a non-steroidal anti-inflammatory (NSAID) drug and widely used analgesic, is recognized as an e...

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Main Authors: N.C. Prachalith, Bibi Raza Khanam, Basavaraj Angadi, H.M. Suresh Kumar, Pravin Kumar, Birendra Singh, U.V. Khadke
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Next Materials
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Online Access:http://www.sciencedirect.com/science/article/pii/S2949822825003338
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author N.C. Prachalith
Bibi Raza Khanam
Basavaraj Angadi
H.M. Suresh Kumar
Pravin Kumar
Birendra Singh
U.V. Khadke
author_facet N.C. Prachalith
Bibi Raza Khanam
Basavaraj Angadi
H.M. Suresh Kumar
Pravin Kumar
Birendra Singh
U.V. Khadke
author_sort N.C. Prachalith
collection DOAJ
description The escalating presence of pharmaceutical pollutants in aquatic ecosystems poses a significant environmental challenge, necessitating the exploration of innovative remediation strategies. Flufenamic acid, a non-steroidal anti-inflammatory (NSAID) drug and widely used analgesic, is recognized as an emerging contaminant due to its incomplete removal in conventional wastewater treatment processes. This research investigates the impact of high-energy gamma irradiation on the structural and optical properties of flufenamic acid to evaluate its potential for water purification and the development of novel chemo-sensors. Flufenamic acid samples were subjected to varying doses of gamma irradiation (0, 25, 50, and 75 kGy) from a 60Co source, and the resulting structural and optical modifications were characterized using XRD, Raman spectroscopy, Fourier-transform infrared spectroscopy, UV-Vis spectroscopy, and fluorescence spectroscopy. XRD analysis confirmed irradiation-induced structural modifications, including a transformation from Form I to Form II, in addition to the changes in lattice parameters, crystallite size, dislocation density, and lattice strain. These modifications were further validated by FTIR spectroscopy and Raman scattering, revealing significant alterations in FLA’s optical properties, as evidenced by UV-absorption, fluorescence, Raman, and FTIR spectroscopy. Notably, the 25 kGy. Irradiated sample exhibited enhanced Urbach energy, indicating increased disorder and chain scissoring, while its lowest absorbance suggested material degradation. Despite these structural changes, the optical energy band gap, derived from Tauc plots, remained unchanged within error bars across all doses. Moreover, a new fluorescence peak at ∼518 nm appeared, attributed to oxygen-related defects. These dose-dependent modifications in FLA’s structure and photoluminescence properties highlight its potential for water purification and the development of a new class of chemo-sensors.
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spelling doaj-art-ab47a7dba4e149378bfb2e711b977aed2025-08-20T02:35:46ZengElsevierNext Materials2949-82282025-07-01810081510.1016/j.nxmate.2025.100815An effective approach for water pollution remediation and structural-optical analysis of gamma-irradiated flufenamic acidN.C. Prachalith0Bibi Raza Khanam1Basavaraj Angadi2H.M. Suresh Kumar3Pravin Kumar4Birendra Singh5U.V. Khadke6Department of Physics, Vijayanagara Sri Krishnadevaraya University, Ballari 583105, IndiaDepartment of Physics, Vijayanagara Sri Krishnadevaraya University, Ballari 583105, IndiaDepartment of Physics, Bangalore University, Bangalore 560056, IndiaDepartment of Physics, Siddaganga Institute of Technology, Tumakuru 572103, IndiaInter University Accelerator Centre, New Delhi 110067, IndiaInter University Accelerator Centre, New Delhi 110067, IndiaDepartment of Physics, Vijayanagara Sri Krishnadevaraya University, Ballari 583105, India; Corresponding author.The escalating presence of pharmaceutical pollutants in aquatic ecosystems poses a significant environmental challenge, necessitating the exploration of innovative remediation strategies. Flufenamic acid, a non-steroidal anti-inflammatory (NSAID) drug and widely used analgesic, is recognized as an emerging contaminant due to its incomplete removal in conventional wastewater treatment processes. This research investigates the impact of high-energy gamma irradiation on the structural and optical properties of flufenamic acid to evaluate its potential for water purification and the development of novel chemo-sensors. Flufenamic acid samples were subjected to varying doses of gamma irradiation (0, 25, 50, and 75 kGy) from a 60Co source, and the resulting structural and optical modifications were characterized using XRD, Raman spectroscopy, Fourier-transform infrared spectroscopy, UV-Vis spectroscopy, and fluorescence spectroscopy. XRD analysis confirmed irradiation-induced structural modifications, including a transformation from Form I to Form II, in addition to the changes in lattice parameters, crystallite size, dislocation density, and lattice strain. These modifications were further validated by FTIR spectroscopy and Raman scattering, revealing significant alterations in FLA’s optical properties, as evidenced by UV-absorption, fluorescence, Raman, and FTIR spectroscopy. Notably, the 25 kGy. Irradiated sample exhibited enhanced Urbach energy, indicating increased disorder and chain scissoring, while its lowest absorbance suggested material degradation. Despite these structural changes, the optical energy band gap, derived from Tauc plots, remained unchanged within error bars across all doses. Moreover, a new fluorescence peak at ∼518 nm appeared, attributed to oxygen-related defects. These dose-dependent modifications in FLA’s structure and photoluminescence properties highlight its potential for water purification and the development of a new class of chemo-sensors.http://www.sciencedirect.com/science/article/pii/S2949822825003338Flufenamic acidγ- irradiationStructuralEnergy gapDegradationPolymorphism
spellingShingle N.C. Prachalith
Bibi Raza Khanam
Basavaraj Angadi
H.M. Suresh Kumar
Pravin Kumar
Birendra Singh
U.V. Khadke
An effective approach for water pollution remediation and structural-optical analysis of gamma-irradiated flufenamic acid
Next Materials
Flufenamic acid
γ- irradiation
Structural
Energy gap
Degradation
Polymorphism
title An effective approach for water pollution remediation and structural-optical analysis of gamma-irradiated flufenamic acid
title_full An effective approach for water pollution remediation and structural-optical analysis of gamma-irradiated flufenamic acid
title_fullStr An effective approach for water pollution remediation and structural-optical analysis of gamma-irradiated flufenamic acid
title_full_unstemmed An effective approach for water pollution remediation and structural-optical analysis of gamma-irradiated flufenamic acid
title_short An effective approach for water pollution remediation and structural-optical analysis of gamma-irradiated flufenamic acid
title_sort effective approach for water pollution remediation and structural optical analysis of gamma irradiated flufenamic acid
topic Flufenamic acid
γ- irradiation
Structural
Energy gap
Degradation
Polymorphism
url http://www.sciencedirect.com/science/article/pii/S2949822825003338
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