Genotype Distribution and High-Risk Factors Analysis of Group B Streptococcus in Late-Stage Pregnant Women in the Linyi Region

Conclusion: The colonization rate of GBS in the reproductive tract of pregnant women in late pregnancy in the Linyi region is 7.07%. Having a college degree or above, absence of pregnancy vomiting, elevated levels of albumin, globulin, direct bilirubin, glutamyl transferase, and total bile acids, an...

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Main Authors: Weiping Zhou, Xiaoyan Chen, Jie Chen, Xiuhua Zheng, Xueqiang Zhang, Yubin Chen, Yuehua Pan, Chunling Ma
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:International Journal of Microbiology
Online Access:http://dx.doi.org/10.1155/ijm/9910073
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author Weiping Zhou
Xiaoyan Chen
Jie Chen
Xiuhua Zheng
Xueqiang Zhang
Yubin Chen
Yuehua Pan
Chunling Ma
author_facet Weiping Zhou
Xiaoyan Chen
Jie Chen
Xiuhua Zheng
Xueqiang Zhang
Yubin Chen
Yuehua Pan
Chunling Ma
author_sort Weiping Zhou
collection DOAJ
description Conclusion: The colonization rate of GBS in the reproductive tract of pregnant women in late pregnancy in the Linyi region is 7.07%. Having a college degree or above, absence of pregnancy vomiting, elevated levels of albumin, globulin, direct bilirubin, glutamyl transferase, and total bile acids, and decreased levels of alkaline phosphatase and lactate dehydrogenase are high-risk factors for GBS infection; ST10, ST19, ST529, and ST862 are the main genotypes prevalent in this region; there are regional differences in the distribution of GBS genotypes and CC groups; there are statistically significant differences in the distribution of virulence factors among GBS strains with different MLST genotypes (p<0.05); GBS shows high sensitivity to penicillin drugs and can still be used as the preferred medication for the prevention and treatment of GBS infection.
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institution Kabale University
issn 1687-9198
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publishDate 2024-01-01
publisher Wiley
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series International Journal of Microbiology
spelling doaj-art-ab397ac142864bed807a97e6f9f875952025-01-04T00:00:07ZengWileyInternational Journal of Microbiology1687-91982024-01-01202410.1155/ijm/9910073Genotype Distribution and High-Risk Factors Analysis of Group B Streptococcus in Late-Stage Pregnant Women in the Linyi RegionWeiping Zhou0Xiaoyan Chen1Jie Chen2Xiuhua Zheng3Xueqiang Zhang4Yubin Chen5Yuehua Pan6Chunling Ma7Clinical LaboratoryClinical LaboratoryClinical LaboratoryClinical LaboratoryClinical LaboratoryClinical LaboratoryClinical LaboratoryKey Laboratory of Birth DefectsConclusion: The colonization rate of GBS in the reproductive tract of pregnant women in late pregnancy in the Linyi region is 7.07%. Having a college degree or above, absence of pregnancy vomiting, elevated levels of albumin, globulin, direct bilirubin, glutamyl transferase, and total bile acids, and decreased levels of alkaline phosphatase and lactate dehydrogenase are high-risk factors for GBS infection; ST10, ST19, ST529, and ST862 are the main genotypes prevalent in this region; there are regional differences in the distribution of GBS genotypes and CC groups; there are statistically significant differences in the distribution of virulence factors among GBS strains with different MLST genotypes (p<0.05); GBS shows high sensitivity to penicillin drugs and can still be used as the preferred medication for the prevention and treatment of GBS infection.http://dx.doi.org/10.1155/ijm/9910073
spellingShingle Weiping Zhou
Xiaoyan Chen
Jie Chen
Xiuhua Zheng
Xueqiang Zhang
Yubin Chen
Yuehua Pan
Chunling Ma
Genotype Distribution and High-Risk Factors Analysis of Group B Streptococcus in Late-Stage Pregnant Women in the Linyi Region
International Journal of Microbiology
title Genotype Distribution and High-Risk Factors Analysis of Group B Streptococcus in Late-Stage Pregnant Women in the Linyi Region
title_full Genotype Distribution and High-Risk Factors Analysis of Group B Streptococcus in Late-Stage Pregnant Women in the Linyi Region
title_fullStr Genotype Distribution and High-Risk Factors Analysis of Group B Streptococcus in Late-Stage Pregnant Women in the Linyi Region
title_full_unstemmed Genotype Distribution and High-Risk Factors Analysis of Group B Streptococcus in Late-Stage Pregnant Women in the Linyi Region
title_short Genotype Distribution and High-Risk Factors Analysis of Group B Streptococcus in Late-Stage Pregnant Women in the Linyi Region
title_sort genotype distribution and high risk factors analysis of group b streptococcus in late stage pregnant women in the linyi region
url http://dx.doi.org/10.1155/ijm/9910073
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