“En-Face” Spectral-Domain Optical Coherence Tomography Findings in Multiple Evanescent White Dot Syndrome

Purpose. The recent use of “en-face” enhanced-depth imaging spectral-domain optical coherence tomography (EDI SD-OCT) helps distinguish the retinal layers involved in the physiopathology of multiple evanescent white dot syndrome (MEWDS). Methods. Four patients presenting with MEWDS underwent a compr...

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Main Authors: Flore De bats, Benjamin Wolff, Vivien Vasseur, Aude Affortit, Laurent Kodjikian, José-Alain Sahel, Martine Mauget-faÿsse
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Journal of Ophthalmology
Online Access:http://dx.doi.org/10.1155/2014/928028
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author Flore De bats
Benjamin Wolff
Vivien Vasseur
Aude Affortit
Laurent Kodjikian
José-Alain Sahel
Martine Mauget-faÿsse
author_facet Flore De bats
Benjamin Wolff
Vivien Vasseur
Aude Affortit
Laurent Kodjikian
José-Alain Sahel
Martine Mauget-faÿsse
author_sort Flore De bats
collection DOAJ
description Purpose. The recent use of “en-face” enhanced-depth imaging spectral-domain optical coherence tomography (EDI SD-OCT) helps distinguish the retinal layers involved in the physiopathology of multiple evanescent white dot syndrome (MEWDS). Methods. Four patients presenting with MEWDS underwent a comprehensive ocular examination including C-scan (“en-face”) EDI SD-OCT at the initial visit and during follow-up. Results. C-scans combined with the other multimodal imaging enabled the visualization of retinal damage. Acute lesions appeared as diffuse and focal disruptions occurring in the ellipsoid and interdigitation zones. The match between autofluorescence imaging, indocyanine green angiography, and “en-face” OCT helped identify the acute microstructural damages in the outer retina further than the choroid. Follow-up using “en-face” EDI-OCT revealed progressive and complete recovery of the central outer retinal layers. Conclusion. “En-face” EDI SD-OCT identified the site of initial damage in MEWDS as the photoreceptors and the interdigitation layers rather than the choroid. Moreover, “en-face” OCT is helpful in the follow-up of these lesions by being able to show the recovery of the outer retinal layers.
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institution Kabale University
issn 2090-004X
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spelling doaj-art-ab24892d9c604cbfa963c083e23448f72025-02-03T05:53:23ZengWileyJournal of Ophthalmology2090-004X2090-00582014-01-01201410.1155/2014/928028928028“En-Face” Spectral-Domain Optical Coherence Tomography Findings in Multiple Evanescent White Dot SyndromeFlore De bats0Benjamin Wolff1Vivien Vasseur2Aude Affortit3Laurent Kodjikian4José-Alain Sahel5Martine Mauget-faÿsse6Department of Ophthalmology, Croix-Rousse University Hospital, Hospices Civils de Lyon, University of Medicine Lyon 1, 103 Grande rue de la Croix Rousse, 69317 Lyon Cedex 04, FranceProfessor Sahel Department, Rothschild Ophthalmologic Foundation, 25 rue Manin, 75019 Paris, FranceProfessor Sahel Department, Rothschild Ophthalmologic Foundation, 25 rue Manin, 75019 Paris, FranceProfessor Sahel Department, Rothschild Ophthalmologic Foundation, 25 rue Manin, 75019 Paris, FranceDepartment of Ophthalmology, Croix-Rousse University Hospital, Hospices Civils de Lyon, University of Medicine Lyon 1, 103 Grande rue de la Croix Rousse, 69317 Lyon Cedex 04, FranceProfessor Sahel Department, Rothschild Ophthalmologic Foundation, 25 rue Manin, 75019 Paris, FranceProfessor Sahel Department, Rothschild Ophthalmologic Foundation, 25 rue Manin, 75019 Paris, FrancePurpose. The recent use of “en-face” enhanced-depth imaging spectral-domain optical coherence tomography (EDI SD-OCT) helps distinguish the retinal layers involved in the physiopathology of multiple evanescent white dot syndrome (MEWDS). Methods. Four patients presenting with MEWDS underwent a comprehensive ocular examination including C-scan (“en-face”) EDI SD-OCT at the initial visit and during follow-up. Results. C-scans combined with the other multimodal imaging enabled the visualization of retinal damage. Acute lesions appeared as diffuse and focal disruptions occurring in the ellipsoid and interdigitation zones. The match between autofluorescence imaging, indocyanine green angiography, and “en-face” OCT helped identify the acute microstructural damages in the outer retina further than the choroid. Follow-up using “en-face” EDI-OCT revealed progressive and complete recovery of the central outer retinal layers. Conclusion. “En-face” EDI SD-OCT identified the site of initial damage in MEWDS as the photoreceptors and the interdigitation layers rather than the choroid. Moreover, “en-face” OCT is helpful in the follow-up of these lesions by being able to show the recovery of the outer retinal layers.http://dx.doi.org/10.1155/2014/928028
spellingShingle Flore De bats
Benjamin Wolff
Vivien Vasseur
Aude Affortit
Laurent Kodjikian
José-Alain Sahel
Martine Mauget-faÿsse
“En-Face” Spectral-Domain Optical Coherence Tomography Findings in Multiple Evanescent White Dot Syndrome
Journal of Ophthalmology
title “En-Face” Spectral-Domain Optical Coherence Tomography Findings in Multiple Evanescent White Dot Syndrome
title_full “En-Face” Spectral-Domain Optical Coherence Tomography Findings in Multiple Evanescent White Dot Syndrome
title_fullStr “En-Face” Spectral-Domain Optical Coherence Tomography Findings in Multiple Evanescent White Dot Syndrome
title_full_unstemmed “En-Face” Spectral-Domain Optical Coherence Tomography Findings in Multiple Evanescent White Dot Syndrome
title_short “En-Face” Spectral-Domain Optical Coherence Tomography Findings in Multiple Evanescent White Dot Syndrome
title_sort en face spectral domain optical coherence tomography findings in multiple evanescent white dot syndrome
url http://dx.doi.org/10.1155/2014/928028
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