Antimicrobial effects of nanocurcumin gel on reducing the microbial count of gingival fluids of implant‒abutment interface: A clinical study
Background. This clinical study aimed to prepare and evaluate the effect of antimicrobial nanocurcumin gel on reducing the microbial counts of gingival fluids of the implant‒abutment interface in patients referred to the Tabriz Faculty of Dentistry for the placement of two dental implants. Methods....
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| Format: | Article |
| Language: | English |
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Tabriz University of Medical Sciences
2022-12-01
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| Series: | Journal of Advanced Periodontology and Implant Dentistry |
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| Online Access: | https://japid.tbzmed.ac.ir/PDF/japid-14-114.pdf |
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| author | Mohammad Ali Ghavimi Shahriar Shahi Solmaz Maleki Dizaj Simin Sharifi Ali Noie Alamdari Amir Reza Jamei Khosroshahi Khadijeh Khezri |
| author_facet | Mohammad Ali Ghavimi Shahriar Shahi Solmaz Maleki Dizaj Simin Sharifi Ali Noie Alamdari Amir Reza Jamei Khosroshahi Khadijeh Khezri |
| author_sort | Mohammad Ali Ghavimi |
| collection | DOAJ |
| description | Background. This clinical study aimed to prepare and evaluate the effect of antimicrobial nanocurcumin gel on reducing the microbial counts of gingival fluids of the implant‒abutment interface in patients referred to the Tabriz Faculty of Dentistry for the placement of two dental implants. Methods. Fifteen patients applying for at least two dental implants were included in the study. During the uncovering session, nanocurcumin gel was placed in one implant, and no substance was placed in another (the control group). Then, in three sessions, implantation sessions (10 days after the repair abutment closure session), prosthesis delivery (15 days after the implantation session), and one month after prosthesis delivery, the patients’ gingival fluid was sampled and cultured to determine bacterial counts in the gingival fluid by colony-forming units (CFU/mL). T-test was used for statistical analysis of data, and statistical significance was set at P<0.05. Results. This study showed that nanocurcumin gel significantly reduced the CFU/mL of gingival fluid in all three sampling stages compared to the control group. Conclusion. According to the results of this study, the application of antimicrobial nanocurcumin gel inside the implant fixture could reduce the microbial counts of gingival fluids. |
| format | Article |
| id | doaj-art-ab0f7705b8584ad7a0b776e250aae7dc |
| institution | Kabale University |
| issn | 2645-5390 |
| language | English |
| publishDate | 2022-12-01 |
| publisher | Tabriz University of Medical Sciences |
| record_format | Article |
| series | Journal of Advanced Periodontology and Implant Dentistry |
| spelling | doaj-art-ab0f7705b8584ad7a0b776e250aae7dc2024-12-10T08:03:00ZengTabriz University of Medical SciencesJournal of Advanced Periodontology and Implant Dentistry2645-53902022-12-0114211411810.34172/japid.2022.014japid-1223Antimicrobial effects of nanocurcumin gel on reducing the microbial count of gingival fluids of implant‒abutment interface: A clinical studyMohammad Ali Ghavimi0Shahriar Shahi1Solmaz Maleki Dizaj2Simin Sharifi3Ali Noie Alamdari4Amir Reza Jamei Khosroshahi5Khadijeh Khezri6Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, IranDental and Periodontal Research Center, Tabriz University of Medical Sciences, Tabriz, IranDental and Periodontal Research Center, Tabriz University of Medical Sciences, Tabriz, IranDental and Periodontal Research Center, Tabriz University of Medical Sciences, Tabriz, IranDepartment of Oral and Maxillofacial Surgery, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, IranDepartment of Pediatric Dentistry, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, IranDeputy of Food and Drug Administration, Urmia University of Medical Sciences, Urmia, IranBackground. This clinical study aimed to prepare and evaluate the effect of antimicrobial nanocurcumin gel on reducing the microbial counts of gingival fluids of the implant‒abutment interface in patients referred to the Tabriz Faculty of Dentistry for the placement of two dental implants. Methods. Fifteen patients applying for at least two dental implants were included in the study. During the uncovering session, nanocurcumin gel was placed in one implant, and no substance was placed in another (the control group). Then, in three sessions, implantation sessions (10 days after the repair abutment closure session), prosthesis delivery (15 days after the implantation session), and one month after prosthesis delivery, the patients’ gingival fluid was sampled and cultured to determine bacterial counts in the gingival fluid by colony-forming units (CFU/mL). T-test was used for statistical analysis of data, and statistical significance was set at P<0.05. Results. This study showed that nanocurcumin gel significantly reduced the CFU/mL of gingival fluid in all three sampling stages compared to the control group. Conclusion. According to the results of this study, the application of antimicrobial nanocurcumin gel inside the implant fixture could reduce the microbial counts of gingival fluids.https://japid.tbzmed.ac.ir/PDF/japid-14-114.pdfantimicrobial agentscurcumindental implantnanogel |
| spellingShingle | Mohammad Ali Ghavimi Shahriar Shahi Solmaz Maleki Dizaj Simin Sharifi Ali Noie Alamdari Amir Reza Jamei Khosroshahi Khadijeh Khezri Antimicrobial effects of nanocurcumin gel on reducing the microbial count of gingival fluids of implant‒abutment interface: A clinical study Journal of Advanced Periodontology and Implant Dentistry antimicrobial agents curcumin dental implant nanogel |
| title | Antimicrobial effects of nanocurcumin gel on reducing the microbial count of gingival fluids of implant‒abutment interface: A clinical study |
| title_full | Antimicrobial effects of nanocurcumin gel on reducing the microbial count of gingival fluids of implant‒abutment interface: A clinical study |
| title_fullStr | Antimicrobial effects of nanocurcumin gel on reducing the microbial count of gingival fluids of implant‒abutment interface: A clinical study |
| title_full_unstemmed | Antimicrobial effects of nanocurcumin gel on reducing the microbial count of gingival fluids of implant‒abutment interface: A clinical study |
| title_short | Antimicrobial effects of nanocurcumin gel on reducing the microbial count of gingival fluids of implant‒abutment interface: A clinical study |
| title_sort | antimicrobial effects of nanocurcumin gel on reducing the microbial count of gingival fluids of implant abutment interface a clinical study |
| topic | antimicrobial agents curcumin dental implant nanogel |
| url | https://japid.tbzmed.ac.ir/PDF/japid-14-114.pdf |
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