Role of Dobutamine Stress Echocardiography in the Evaluation of Patients Undergoing Noncardiac Surgeries in the Contemporary Era

Objective: Dobutamine stress echocardiography (DSE) is a widely used diagnostic modality for preoperative cardiac risk assessment in patients undergoing major noncardiac surgeries. However, its role in facilitating safe noncardiac surgery in the contemporary era needs to be evaluated. Materials and...

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Main Authors: Tanu Chaudhary, Manish Bansal, Ravi R. Kasliwal
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-12-01
Series:Journal of the Indian Academy of Echocardiography & Cardiovascular Imaging
Subjects:
Online Access:https://journals.lww.com/10.4103/jiae.jiae_40_24
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author Tanu Chaudhary
Manish Bansal
Ravi R. Kasliwal
author_facet Tanu Chaudhary
Manish Bansal
Ravi R. Kasliwal
author_sort Tanu Chaudhary
collection DOAJ
description Objective: Dobutamine stress echocardiography (DSE) is a widely used diagnostic modality for preoperative cardiac risk assessment in patients undergoing major noncardiac surgeries. However, its role in facilitating safe noncardiac surgery in the contemporary era needs to be evaluated. Materials and Methods: A total of 1283 participants (mean age – 63.8 years and 54.9% males) undergoing DSE for preoperative cardiac evaluation before nonemergent, noncardiac, major surgeries were included. DSE findings were recorded, and the Revised Cardiac Risk Index or Lee’s score was also calculated. The patients were followed up for in-hospital adverse cardiac events. Results: DSE showed evidence of inducible myocardial ischemia in 19 (1.5%) patients, whereas Lee’s score was elevated (>3) in 43 (3.4%) patients. The overall in-hospital event rate was 0.7%. Among 1264 patients with normal DSE, 5 (0.4%) had a perioperative cardiac event (negative predictive value 99.6%). Of the 19 patients with abnormal DSE, all underwent coronary angiography which was abnormal in 16 patients. Of these 16 patients, 4 had a perioperative cardiac event. A Lee’s score value >3 had a sensitivity of 68.4% (95% confidence interval [CI] - 43.5–87.4), specificity of 97.6% (95% CI - 96.6–98.4), positive predictive value of 30.2% (95% CI - 21.4–40.9), and negative predictive value of 99.5% (95% CI - 99.1–99.8) for predicting abnormal DSE. Conclusion: Our study reinforces the clinical utility of DSE in facilitating major, nonemergent, noncardiac surgeries in a contemporary setting in India. A normal DSE had a very high negative predictive value for an adverse cardiac event, whereas an abnormal DSE identified the population at high risk for perioperative cardiac events requiring appropriate risk mitigation strategies.
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spelling doaj-art-aae5385f3d904e53afd7c56cb0b5f5282025-01-12T10:18:45ZengWolters Kluwer Medknow PublicationsJournal of the Indian Academy of Echocardiography & Cardiovascular Imaging2543-14632543-14712024-12-018315916310.4103/jiae.jiae_40_24Role of Dobutamine Stress Echocardiography in the Evaluation of Patients Undergoing Noncardiac Surgeries in the Contemporary EraTanu ChaudharyManish BansalRavi R. KasliwalObjective: Dobutamine stress echocardiography (DSE) is a widely used diagnostic modality for preoperative cardiac risk assessment in patients undergoing major noncardiac surgeries. However, its role in facilitating safe noncardiac surgery in the contemporary era needs to be evaluated. Materials and Methods: A total of 1283 participants (mean age – 63.8 years and 54.9% males) undergoing DSE for preoperative cardiac evaluation before nonemergent, noncardiac, major surgeries were included. DSE findings were recorded, and the Revised Cardiac Risk Index or Lee’s score was also calculated. The patients were followed up for in-hospital adverse cardiac events. Results: DSE showed evidence of inducible myocardial ischemia in 19 (1.5%) patients, whereas Lee’s score was elevated (>3) in 43 (3.4%) patients. The overall in-hospital event rate was 0.7%. Among 1264 patients with normal DSE, 5 (0.4%) had a perioperative cardiac event (negative predictive value 99.6%). Of the 19 patients with abnormal DSE, all underwent coronary angiography which was abnormal in 16 patients. Of these 16 patients, 4 had a perioperative cardiac event. A Lee’s score value >3 had a sensitivity of 68.4% (95% confidence interval [CI] - 43.5–87.4), specificity of 97.6% (95% CI - 96.6–98.4), positive predictive value of 30.2% (95% CI - 21.4–40.9), and negative predictive value of 99.5% (95% CI - 99.1–99.8) for predicting abnormal DSE. Conclusion: Our study reinforces the clinical utility of DSE in facilitating major, nonemergent, noncardiac surgeries in a contemporary setting in India. A normal DSE had a very high negative predictive value for an adverse cardiac event, whereas an abnormal DSE identified the population at high risk for perioperative cardiac events requiring appropriate risk mitigation strategies.https://journals.lww.com/10.4103/jiae.jiae_40_24cardiac risk assessmentlee’s scorenoncardiac surgery
spellingShingle Tanu Chaudhary
Manish Bansal
Ravi R. Kasliwal
Role of Dobutamine Stress Echocardiography in the Evaluation of Patients Undergoing Noncardiac Surgeries in the Contemporary Era
Journal of the Indian Academy of Echocardiography & Cardiovascular Imaging
cardiac risk assessment
lee’s score
noncardiac surgery
title Role of Dobutamine Stress Echocardiography in the Evaluation of Patients Undergoing Noncardiac Surgeries in the Contemporary Era
title_full Role of Dobutamine Stress Echocardiography in the Evaluation of Patients Undergoing Noncardiac Surgeries in the Contemporary Era
title_fullStr Role of Dobutamine Stress Echocardiography in the Evaluation of Patients Undergoing Noncardiac Surgeries in the Contemporary Era
title_full_unstemmed Role of Dobutamine Stress Echocardiography in the Evaluation of Patients Undergoing Noncardiac Surgeries in the Contemporary Era
title_short Role of Dobutamine Stress Echocardiography in the Evaluation of Patients Undergoing Noncardiac Surgeries in the Contemporary Era
title_sort role of dobutamine stress echocardiography in the evaluation of patients undergoing noncardiac surgeries in the contemporary era
topic cardiac risk assessment
lee’s score
noncardiac surgery
url https://journals.lww.com/10.4103/jiae.jiae_40_24
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AT manishbansal roleofdobutaminestressechocardiographyintheevaluationofpatientsundergoingnoncardiacsurgeriesinthecontemporaryera
AT ravirkasliwal roleofdobutaminestressechocardiographyintheevaluationofpatientsundergoingnoncardiacsurgeriesinthecontemporaryera