Synaptic signatures and disease vulnerabilities of layer 5 pyramidal neurons

Synaptic signatures and disease vulnerabilities of layer 5 pyramidal neurons

Abstract Cortical layer 5 (L5) intratelencephalic (IT) and pyramidal tract (PT) neurons are embedded in distinct information processing pathways. Their morphology, connectivity, electrophysiological properties, and role in behavior have been extensively analyzed. However, the molecular composition o...

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Main Authors: Gabriele Marcassa, Dan Dascenco, Blanca Lorente-Echeverría, Danie Daaboul, Jeroen Vandensteen, Elke Leysen, Lucas Baltussen, Andrew J. M. Howden, Joris de Wit
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-55470-w
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