Footprint-C reveals transcription factor modes in local clusters and long-range chromatin interactions

Abstract The proximity ligation-based Hi-C and derivative methods are the mainstream tools to study genome-wide chromatin interactions. These methods often fragment the genome using enzymes functionally irrelevant to the interactions per se, restraining the efficiency in identifying structural featu...

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Bibliographic Details
Main Authors: Xiaokun Liu, Hanhan Wei, Qifan Zhang, Na Zhang, Qingqing Wu, Chenhuan Xu
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-55403-7
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