Association between dietary index for gut microbiota and hypertension: a large cross-sectional study from NHANES
Background Gut microbiota is strongly associated with hypertension. The Dietary Index of Gut Microbiota (DI-GM) is a newly proposed indicator of the diversity of gut microbiota in the diet. However, the relationship between DI-GM and hypertension is unclear.Methods Data for this study were obtained...
Saved in:
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMJ Publishing Group
|
| Series: | BMJ Nutrition, Prevention & Health |
| Online Access: | https://nutrition.bmj.com/content/early/2025/06/13/bmjnph-2024-001163.full |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | Background Gut microbiota is strongly associated with hypertension. The Dietary Index of Gut Microbiota (DI-GM) is a newly proposed indicator of the diversity of gut microbiota in the diet. However, the relationship between DI-GM and hypertension is unclear.Methods Data for this study were obtained from the National Health and Nutrition Examination Survey (2007–2020). Dietary data were used to calculate DI-GM and grouped into three tertile groups. Survey logistic regression and restricted cubic spline (RCS) were used to analyse the association between DI-GM and hypertension.Results A total of 20 804 participants (age ≥20 years) were enrolled in the study. After adjusting for all covariates, the ORs for hypertension in the medium DI-GM group (second quartile, 4–5) and high DI-GM group (third quartile, >5) were 0.94 (95% CI: 0.83 to 1.06) and 0.87 (95% CI: 0.76 to 0.99) compared with the low DI-GM group (first quartile, <4). Additionally, results from the RCS analysis indicated a linear association between DI-GM and hypertension (p value for non-linearity=0.57).Conclusion Our findings suggest that higher DI-GM dietary patterns are associated with a lower prevalence of hypertension in a representative sample of US adults. These results suggest that dietary patterns characterised by a higher DI-GM may represent a potential strategy for the prevention of hypertension. |
|---|---|
| ISSN: | 2516-5542 |