Role of the TGF-β/Smad3 pathway in pancreatic cancer cell growth and stem cell characteristics
Abstract Pancreatic cancer (PC) is a highly malignant digestive system tumor with poor prognosis, and cancer stem cell (CSC) is known to drive its progression, metastasis, and recurrence. The transforming growth factor-β (TGF-β)/small mothers against decapentaplegic 3 (Smad3) signaling is implicated...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Springer
2025-08-01
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| Series: | Discover Oncology |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/s12672-025-03220-9 |
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