Time-course of host cell transcription during the HTLV-1 transcriptional burst.

Time-course of host cell transcription during the HTLV-1 transcriptional burst.

The human T-cell leukemia virus type 1 (HTLV-1) transactivator protein Tax has pleiotropic functions in the host cell affecting cell-cycle regulation, DNA damage response pathways and apoptosis. These actions of Tax have been implicated in the persistence and pathogenesis of HTLV-1-infected cells. I...

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Bibliographic Details
Main Authors: Helen Kiik, Saumya Ramanayake, Michi Miura, Yuetsu Tanaka, Anat Melamed, Charles R M Bangham
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-05-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1010387&type=printable
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