Orchard: Building large cancer phylogenies using stochastic combinatorial search.
Phylogenies depicting the evolutionary history of genetically heterogeneous subpopulations of cells from the same cancer, i.e., cancer phylogenies, offer valuable insights about cancer development and guide treatment strategies. Many methods exist that reconstruct cancer phylogenies using point muta...
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Main Authors: | Ethan Kulman, Rui Kuang, Quaid Morris |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2024-12-01
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Series: | PLoS Computational Biology |
Online Access: | https://doi.org/10.1371/journal.pcbi.1012653 |
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