To compare the efficacy of hyperbaric levobupivacaine (0.5%) versus hyperbaric bupivacaine (0.5%) in the subarachnoid block for infraumbilical surgeries

Background: Spinal anesthesia is the neuraxial regional anesthesia technique used in infraumbilical surgeries such as inguinal hernia, hydrocele, hysterectomy, and lower limb surgeries. Levobupivacaine and bupivacaine are local anesthetic agents used for spinal anesthesia. Aims and Objectives: Th...

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Main Authors: Rachna Gupta, Jitendra Agrawal, Preeti Goyal, Shreya Putta, Bharat Tarachandani
Format: Article
Language:English
Published: Manipal College of Medical Sciences, Pokhara 2024-12-01
Series:Asian Journal of Medical Sciences
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Online Access:https://www.nepjol.info/index.php/AJMS/article/view/71040
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author Rachna Gupta
Jitendra Agrawal
Preeti Goyal
Shreya Putta
Bharat Tarachandani
author_facet Rachna Gupta
Jitendra Agrawal
Preeti Goyal
Shreya Putta
Bharat Tarachandani
author_sort Rachna Gupta
collection DOAJ
description Background: Spinal anesthesia is the neuraxial regional anesthesia technique used in infraumbilical surgeries such as inguinal hernia, hydrocele, hysterectomy, and lower limb surgeries. Levobupivacaine and bupivacaine are local anesthetic agents used for spinal anesthesia. Aims and Objectives: The aim of the study was to compare the efficacy of hyperbaric levobupivacaine (0.5%) versus hyperbaric bupivacaine (0.5%) in subarachnoid blocks for infraumbilical surgeries. Materials and Methods: A total of 112 patients with American Society of Anesthesiologists grades 1 and 2 scheduled for infraumbilical surgeries were randomly divided into two groups. Group L received 3 mL of hyperbaric levobupivacaine, and group B received 3 mL of hyperbaric bupivacaine intrathecally. The onset of sensory block, onset, and duration of motor block, duration of analgesia and time of first rescue analgesia, hemodynamic parameters, and post-operative side effects, if any, were recorded. Results: The time of onset of sensory block at T10 for group L was 03.16±00.29 min and for group B was 02.16±00.27 min and the time of onset of motor block was higher in group L (03.29±00.32 min) compared to group B (02.45±00.32 min). Duration of motor block was significantly shorter in group L (209.80±6.44 min) compared to group B (252.41±11.49 min). All these findings were statistically significant. Conclusion: Levobupivacaine had a delayed onset of sensory and motor block as compared to bupivacaine, but due to its short duration of motor block and better hemodynamic profile, it seems to be a better alternative to bupivacaine.
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language English
publishDate 2024-12-01
publisher Manipal College of Medical Sciences, Pokhara
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spelling doaj-art-a8c3eae921aa47149ce0402b1aac6f7c2024-12-05T04:17:54ZengManipal College of Medical Sciences, PokharaAsian Journal of Medical Sciences2467-91002091-05762024-12-0115124550https://doi.org/10.3126/ajms.v15i12.71040To compare the efficacy of hyperbaric levobupivacaine (0.5%) versus hyperbaric bupivacaine (0.5%) in the subarachnoid block for infraumbilical surgeriesRachna Gupta 0https://orcid.org/0009-0006-6006-4614Jitendra Agrawal 1https://orcid.org/0009-0001-2470-4761Preeti Goyal 2https://orcid.org/0000-0002-6057-4781Shreya Putta 3https://orcid.org/0009-0003-1385-7011Bharat Tarachandani 4https://orcid.org/0009-0001-6739-9429Postgraduate Resident, Department of Anaesthesiology, Gajra Raja Medical College, Gwalior, Madhya Pradesh, India Professor, Department of Anaesthesiology, Gajra Raja Medical College, Gwalior, Madhya Pradesh, India Professor and Head, Department of Anaesthesiology, Gajra Raja Medical College, Gwalior, Madhya Pradesh, India Postgraduate Resident, Department of Anaesthesiology, Gajra Raja Medical College, Gwalior, Madhya Pradesh, India Postgraduate Resident, Department of Anaesthesiology, Gajra Raja Medical College, Gwalior, Madhya Pradesh, India Background: Spinal anesthesia is the neuraxial regional anesthesia technique used in infraumbilical surgeries such as inguinal hernia, hydrocele, hysterectomy, and lower limb surgeries. Levobupivacaine and bupivacaine are local anesthetic agents used for spinal anesthesia. Aims and Objectives: The aim of the study was to compare the efficacy of hyperbaric levobupivacaine (0.5%) versus hyperbaric bupivacaine (0.5%) in subarachnoid blocks for infraumbilical surgeries. Materials and Methods: A total of 112 patients with American Society of Anesthesiologists grades 1 and 2 scheduled for infraumbilical surgeries were randomly divided into two groups. Group L received 3 mL of hyperbaric levobupivacaine, and group B received 3 mL of hyperbaric bupivacaine intrathecally. The onset of sensory block, onset, and duration of motor block, duration of analgesia and time of first rescue analgesia, hemodynamic parameters, and post-operative side effects, if any, were recorded. Results: The time of onset of sensory block at T10 for group L was 03.16±00.29 min and for group B was 02.16±00.27 min and the time of onset of motor block was higher in group L (03.29±00.32 min) compared to group B (02.45±00.32 min). Duration of motor block was significantly shorter in group L (209.80±6.44 min) compared to group B (252.41±11.49 min). All these findings were statistically significant. Conclusion: Levobupivacaine had a delayed onset of sensory and motor block as compared to bupivacaine, but due to its short duration of motor block and better hemodynamic profile, it seems to be a better alternative to bupivacaine.https://www.nepjol.info/index.php/AJMS/article/view/71040levobupivacaine; bupivacaine; subarachnoid block
spellingShingle Rachna Gupta
Jitendra Agrawal
Preeti Goyal
Shreya Putta
Bharat Tarachandani
To compare the efficacy of hyperbaric levobupivacaine (0.5%) versus hyperbaric bupivacaine (0.5%) in the subarachnoid block for infraumbilical surgeries
Asian Journal of Medical Sciences
levobupivacaine; bupivacaine; subarachnoid block
title To compare the efficacy of hyperbaric levobupivacaine (0.5%) versus hyperbaric bupivacaine (0.5%) in the subarachnoid block for infraumbilical surgeries
title_full To compare the efficacy of hyperbaric levobupivacaine (0.5%) versus hyperbaric bupivacaine (0.5%) in the subarachnoid block for infraumbilical surgeries
title_fullStr To compare the efficacy of hyperbaric levobupivacaine (0.5%) versus hyperbaric bupivacaine (0.5%) in the subarachnoid block for infraumbilical surgeries
title_full_unstemmed To compare the efficacy of hyperbaric levobupivacaine (0.5%) versus hyperbaric bupivacaine (0.5%) in the subarachnoid block for infraumbilical surgeries
title_short To compare the efficacy of hyperbaric levobupivacaine (0.5%) versus hyperbaric bupivacaine (0.5%) in the subarachnoid block for infraumbilical surgeries
title_sort to compare the efficacy of hyperbaric levobupivacaine 0 5 versus hyperbaric bupivacaine 0 5 in the subarachnoid block for infraumbilical surgeries
topic levobupivacaine; bupivacaine; subarachnoid block
url https://www.nepjol.info/index.php/AJMS/article/view/71040
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