Mild encephalitis/encephalopathy with reversible splenial lesion (MERS) associated with respiratory syncytial virus and Pseudomonas putida infection: A case report
Background: Clinically mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) is a mild encephalopathy, which may be associated with various pathogens, including virus and bacteria. However, there have been no reports on MERS associated with co-infection by respiratory syncytial v...
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Elsevier
2024-10-01
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| author | Yanxiang Chen Kai Dai Bofu Ruan Hui Wang Guonan Zhou Ying Jiang |
| author_facet | Yanxiang Chen Kai Dai Bofu Ruan Hui Wang Guonan Zhou Ying Jiang |
| author_sort | Yanxiang Chen |
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| description | Background: Clinically mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) is a mild encephalopathy, which may be associated with various pathogens, including virus and bacteria. However, there have been no reports on MERS associated with co-infection by respiratory syncytial virus (RSV) or Pseudomonas putida in adults. Case presentation: We reported a 29-year-old Chinese woman with MERS associated with RSV and Pseudomonas putida. This woman presented with fever, sore throat, cough, and altered mental states. The results of RSV-RNA in the specimens from throat and sputum culture of Pseudomonas putida were positive. The initial head CT scan on the day of admission revealed abnormal hypodense lesions in the suprasellar cistern (SCC). Subsequent brain magnetic resonance imaging (MRI) also demonstrated abnormal hypersignals in the same region. The patient's altered mental status improved on day after ceftriaxone and low-dose corticosteroid therapy. The SCC hypersignal on MRI completely resolved after three weeks, and no recurrence of symptoms occurred during the two-month follow-up period. Conclusions: It is the first reported case of MERS associated with RSV and Pseudomonas putida in the adult, which broadens the spectrum of potential etiologies in MERS. When a patient with a respiratory tract infection presents with neurological symptoms, the possibility of MERS should be considered. |
| format | Article |
| id | doaj-art-a8c3397678e240a0bc779d1585ea91e1 |
| institution | Kabale University |
| issn | 2405-8440 |
| language | English |
| publishDate | 2024-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj-art-a8c3397678e240a0bc779d1585ea91e12024-11-12T05:21:10ZengElsevierHeliyon2405-84402024-10-011020e39685Mild encephalitis/encephalopathy with reversible splenial lesion (MERS) associated with respiratory syncytial virus and Pseudomonas putida infection: A case reportYanxiang Chen0Kai Dai1Bofu Ruan2Hui Wang3Guonan Zhou4Ying Jiang5Department of Neurology, Xiaolan People's Hospital of ZhongShan (The Fifth People's Hospital of ZhongShan), 65#, Middle Section of Jucheng Avenue, Xiaolan, Zhongshan, Guangdong Province, 528400, ChinaDepartment of Neurology, The Third Affiliated Hospital of Sun Yat-sen University, 600# Tianhe Road, Guangzhou, Guangdong Province, 510630, ChinaDepartment of Neurology, Xiaolan People's Hospital of ZhongShan (The Fifth People's Hospital of ZhongShan), 65#, Middle Section of Jucheng Avenue, Xiaolan, Zhongshan, Guangdong Province, 528400, ChinaDepartment of Neurology, Xiaolan People's Hospital of ZhongShan (The Fifth People's Hospital of ZhongShan), 65#, Middle Section of Jucheng Avenue, Xiaolan, Zhongshan, Guangdong Province, 528400, ChinaDepartment of Encephalopathy, Zhongshan Chenxinghai Hospital of Integrated Traditional Chinese and Western Medicine, 18# Zhuyuan Road, Zhongshan, Guangdong Province, 528400, ChinaDepartment of Neurology, The Third Affiliated Hospital of Sun Yat-sen University, 600# Tianhe Road, Guangzhou, Guangdong Province, 510630, China; Corresponding author.Background: Clinically mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) is a mild encephalopathy, which may be associated with various pathogens, including virus and bacteria. However, there have been no reports on MERS associated with co-infection by respiratory syncytial virus (RSV) or Pseudomonas putida in adults. Case presentation: We reported a 29-year-old Chinese woman with MERS associated with RSV and Pseudomonas putida. This woman presented with fever, sore throat, cough, and altered mental states. The results of RSV-RNA in the specimens from throat and sputum culture of Pseudomonas putida were positive. The initial head CT scan on the day of admission revealed abnormal hypodense lesions in the suprasellar cistern (SCC). Subsequent brain magnetic resonance imaging (MRI) also demonstrated abnormal hypersignals in the same region. The patient's altered mental status improved on day after ceftriaxone and low-dose corticosteroid therapy. The SCC hypersignal on MRI completely resolved after three weeks, and no recurrence of symptoms occurred during the two-month follow-up period. Conclusions: It is the first reported case of MERS associated with RSV and Pseudomonas putida in the adult, which broadens the spectrum of potential etiologies in MERS. When a patient with a respiratory tract infection presents with neurological symptoms, the possibility of MERS should be considered.http://www.sciencedirect.com/science/article/pii/S2405844024157167EncephalitisPseudomonas putidaRespiratory syncytial virusReversible splenial lesion |
| spellingShingle | Yanxiang Chen Kai Dai Bofu Ruan Hui Wang Guonan Zhou Ying Jiang Mild encephalitis/encephalopathy with reversible splenial lesion (MERS) associated with respiratory syncytial virus and Pseudomonas putida infection: A case report Heliyon Encephalitis Pseudomonas putida Respiratory syncytial virus Reversible splenial lesion |
| title | Mild encephalitis/encephalopathy with reversible splenial lesion (MERS) associated with respiratory syncytial virus and Pseudomonas putida infection: A case report |
| title_full | Mild encephalitis/encephalopathy with reversible splenial lesion (MERS) associated with respiratory syncytial virus and Pseudomonas putida infection: A case report |
| title_fullStr | Mild encephalitis/encephalopathy with reversible splenial lesion (MERS) associated with respiratory syncytial virus and Pseudomonas putida infection: A case report |
| title_full_unstemmed | Mild encephalitis/encephalopathy with reversible splenial lesion (MERS) associated with respiratory syncytial virus and Pseudomonas putida infection: A case report |
| title_short | Mild encephalitis/encephalopathy with reversible splenial lesion (MERS) associated with respiratory syncytial virus and Pseudomonas putida infection: A case report |
| title_sort | mild encephalitis encephalopathy with reversible splenial lesion mers associated with respiratory syncytial virus and pseudomonas putida infection a case report |
| topic | Encephalitis Pseudomonas putida Respiratory syncytial virus Reversible splenial lesion |
| url | http://www.sciencedirect.com/science/article/pii/S2405844024157167 |
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