Evaluating the Efficacy of Transoral Robotic Surgery (TORS) Versus Radiotherapy, Chemotherapy, and Open Surgery in Treating Oropharyngeal Squamous Cell Carcinoma (OPSCC): A Systematic Review of Reviews

Introduction: Transoral robotic surgery (TORS) is a minimally invasive surgical approach for oropharyngeal squamous cell carcinoma (OPSCC) that aims to reduce morbidity and improve patients' quality of life without compromising oncological outcomes. In this study, we investigate the use of T...

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Bibliographic Details
Main Authors: Abdulrhman Alsayeg, Maha Naif Alshammari, Abdulrahman Mesfer Alajmi, Reem Faihan Alotaibi
Format: Article
Language:English
Published: Riyadh Second Health Cluster Research Center, King Fahad Medical City (KFMC) 2024-12-01
Series:The Journal of Medicine, Law & Public Health
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Online Access:https://jmlph.net/index.php/jmlph/article/view/154
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Summary:Introduction: Transoral robotic surgery (TORS) is a minimally invasive surgical approach for oropharyngeal squamous cell carcinoma (OPSCC) that aims to reduce morbidity and improve patients' quality of life without compromising oncological outcomes. In this study, we investigate the use of TORS in the management of OPSCC and compare it with intensity-modulated radiation therapy (IMRT), concurrent chemoradiation therapy (CCRT), and open surgery. Method: We conducted a systematic review of systematic reviews using PubMed, Cochrane databases, and grey literature. We also searched the reference lists of these articles. The keywords used were "trans-oral robotic surgery" OR "TORS" AND "oropharynx" OR "oropharyngeal cancer". The inclusion criteria were systematic reviews of human studies that focused on patients diagnosed with OPSCC. We excluded non-English articles without translations and articles that did not meet the inclusion criteria. Result: Our review included a total of 10 studies, comprising 16,917 patients. TORS was found to have better oncological outcomes than other modalities, and was associated with similar overall survival and disease-free survival rates as IMRT and CCRT. Additionally, TORS was associated with less postoperative bleeding than open surgery. Conclusion: Our findings suggest that TORS is a safe and effective treatment option for OPSCC. It may be a good option for patients seeking a minimally invasive approach with less postoperative bleeding.
ISSN:2788-9815
2788-791X