Bullous Pyoderma Gangrenosum Associated with Antiphospholipid Syndrome: A Case Report and Literature Review
We report a rare case of a middle-aged Omani woman who was known to have primary antiphospholipid syndrome, glucose-6-phosphate dehydrogenase deficiency, and iron deficiency anemia. Cannulation attempts caused bulla which progressed to ulceration. A pathergy phenomenon with high suspicion of pyoderm...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Oman Medical Specialty Board
2024-07-01
|
| Series: | Oman Medical Journal |
| Subjects: | |
| Online Access: | https://omjournal.org/articleDetails.aspx?coType=1&aId=3801 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1841553543138377728 |
|---|---|
| author | Yousuf Alwashahi Mayar Al-Bahrani Ahmed Almoqbali Asma Alajmi |
| author_facet | Yousuf Alwashahi Mayar Al-Bahrani Ahmed Almoqbali Asma Alajmi |
| author_sort | Yousuf Alwashahi |
| collection | DOAJ |
| description | We report a rare case of a middle-aged Omani woman who was known to have primary antiphospholipid syndrome, glucose-6-phosphate dehydrogenase deficiency, and iron deficiency anemia. Cannulation attempts caused bulla which progressed to ulceration. A pathergy phenomenon with high suspicion of pyoderma gangrenosum was postulated. Management with corticosteroids, cyclosporin, and finally ustekinumab, a novel biologic agent, yielded a beneficial response.
|
| format | Article |
| id | doaj-art-a8aee38377054f669b48ce3cdd4d17a2 |
| institution | Kabale University |
| issn | 1999-768X 2070-5204 |
| language | English |
| publishDate | 2024-07-01 |
| publisher | Oman Medical Specialty Board |
| record_format | Article |
| series | Oman Medical Journal |
| spelling | doaj-art-a8aee38377054f669b48ce3cdd4d17a22025-01-09T07:23:09ZengOman Medical Specialty BoardOman Medical Journal1999-768X2070-52042024-07-01394e658e65810.5001/omj.2024.26Bullous Pyoderma Gangrenosum Associated with Antiphospholipid Syndrome: A Case Report and Literature ReviewYousuf Alwashahi0Mayar Al-Bahrani1Ahmed Almoqbali2Asma Alajmi3Department of Dermatology, Directorate of General Health North Al Batinah, Sohar, OmanFamily Medicine General Foundation Program, Oman Medical Specialty Board, Muscat, OmanDepartment of Medicine, Directorate of General Health North Al Batinah, Sohar, OmanFamily Medicine General Foundation Program, Oman Medical Specialty Board, Muscat, OmanWe report a rare case of a middle-aged Omani woman who was known to have primary antiphospholipid syndrome, glucose-6-phosphate dehydrogenase deficiency, and iron deficiency anemia. Cannulation attempts caused bulla which progressed to ulceration. A pathergy phenomenon with high suspicion of pyoderma gangrenosum was postulated. Management with corticosteroids, cyclosporin, and finally ustekinumab, a novel biologic agent, yielded a beneficial response. https://omjournal.org/articleDetails.aspx?coType=1&aId=3801antiphospholipid syndromepyoderma gangrenosumbullous lesionustekinumaboman |
| spellingShingle | Yousuf Alwashahi Mayar Al-Bahrani Ahmed Almoqbali Asma Alajmi Bullous Pyoderma Gangrenosum Associated with Antiphospholipid Syndrome: A Case Report and Literature Review Oman Medical Journal antiphospholipid syndrome pyoderma gangrenosum bullous lesion ustekinumab oman |
| title | Bullous Pyoderma Gangrenosum Associated with Antiphospholipid Syndrome: A Case Report and Literature Review |
| title_full | Bullous Pyoderma Gangrenosum Associated with Antiphospholipid Syndrome: A Case Report and Literature Review |
| title_fullStr | Bullous Pyoderma Gangrenosum Associated with Antiphospholipid Syndrome: A Case Report and Literature Review |
| title_full_unstemmed | Bullous Pyoderma Gangrenosum Associated with Antiphospholipid Syndrome: A Case Report and Literature Review |
| title_short | Bullous Pyoderma Gangrenosum Associated with Antiphospholipid Syndrome: A Case Report and Literature Review |
| title_sort | bullous pyoderma gangrenosum associated with antiphospholipid syndrome a case report and literature review |
| topic | antiphospholipid syndrome pyoderma gangrenosum bullous lesion ustekinumab oman |
| url | https://omjournal.org/articleDetails.aspx?coType=1&aId=3801 |
| work_keys_str_mv | AT yousufalwashahi bullouspyodermagangrenosumassociatedwithantiphospholipidsyndromeacasereportandliteraturereview AT mayaralbahrani bullouspyodermagangrenosumassociatedwithantiphospholipidsyndromeacasereportandliteraturereview AT ahmedalmoqbali bullouspyodermagangrenosumassociatedwithantiphospholipidsyndromeacasereportandliteraturereview AT asmaalajmi bullouspyodermagangrenosumassociatedwithantiphospholipidsyndromeacasereportandliteraturereview |