Pathological characterization of lung fibrosis in Sprague–Dawley rats treated with fluoro-edenite fibres by intrapleural injection

Pathological characterization of lung fibrosis in Sprague–Dawley rats treated with fluoro-edenite fibres by intrapleural injection

Abstract Background An increased incidence of pleural mesotheliomas in Biancavilla (Italy) was attributed to the environmental exposure to fluoro-edenite (FE). Results from the Ramazzini Institute (RI) in vivo long-term study confirmed the evidence that exposure to FE fibres is correlated with an in...

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Bibliographic Details
Main Authors: Eva Tibaldi, Federica Gnudi, Daniele Mandrioli, Caterina Bruno, Amerigo Zona, Lucia Fazzo, Pietro Comba
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Journal of Occupational Medicine and Toxicology
Subjects:
Fluoro-Edenite
Mesothelioma
Fibrosis
Ashcroft quantification
Immunohistochemistry
Online Access:https://doi.org/10.1186/s12995-024-00434-5
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