Influence of Donor Thickness on Visual Acuity in Descemet’s Stripping Automated Endothelial Keratoplasty

Abstract Purpose: Conventional Descemet's Stripping Automated Endothelial Keratoplasty (DSAEK) is a corneal transplantation procedure where the patient's inner dysfunctional layer is replaced with donor lamella. The data currently present in the literature about the correlation between lam...

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Main Authors: Tomislav Kuzman, Ana Meter, Miro Kalauz, Sanja Masnec, Ivan Škegro, Ivana Jonjić
Format: Article
Language:English
Published: Knowledge E 2022-11-01
Series:Journal of Ophthalmic & Vision Research
Subjects:
Online Access:https://doi.org/10.18502/jovr.v17i4.12296
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author Tomislav Kuzman
Ana Meter
Miro Kalauz
Sanja Masnec
Ivan Škegro
Ivana Jonjić
author_facet Tomislav Kuzman
Ana Meter
Miro Kalauz
Sanja Masnec
Ivan Škegro
Ivana Jonjić
author_sort Tomislav Kuzman
collection DOAJ
description Abstract Purpose: Conventional Descemet's Stripping Automated Endothelial Keratoplasty (DSAEK) is a corneal transplantation procedure where the patient's inner dysfunctional layer is replaced with donor lamella. The data currently present in the literature about the correlation between lamellar thickness and visual acuity is sometimes contradictory and lacks clarity. Methods: Study included 55 eyes that underwent the conventional DSAEK procedure. Patients had no other comorbidities that could affect visual acuity. Data about lamellar thickness and visual acuity were measured six months after surgery with anterior segment optical coherent tomography (A5-OCT). Results: The results show that visual acuity before surgery improved from 0.82 to 0.25 logMAR after surgery. Better visual acuity of 0.20 logMAR was achieved with postoperative lamellas thinner than 124 μm, while statistically significantly lower visual acuity of 0.29 logMAR was gained with postoperative lamellas thicker than 124 μm. Conclusion: Our results suggest that the goal after conventional DSAEK is to have postoperative lamellas thinner than 124 μm in the eye, as this will result in better postoperative visual acuity. This value represents the optimal thickness for conventional DSAEK surgery that could minimize tissue loss for eye banks and surgeons may experience fewer problems during surgery, while obtaining good final visual acuity.
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spelling doaj-art-a88e7a02652142e48e582c60a9e10c7c2025-01-13T07:14:26ZengKnowledge EJournal of Ophthalmic & Vision Research2008-20102008-322X2022-11-0117446246910.18502/jovr.v17i4.12296jovr.v17i4.12296Influence of Donor Thickness on Visual Acuity in Descemet’s Stripping Automated Endothelial KeratoplastyTomislav Kuzman0Ana Meter1Miro Kalauz2Sanja Masnec3Ivan Škegro4Ivana Jonjić Department of Ophthalmology, University Hospital Center Zagreb, Zagreb, Croatia Department of Ophthalmology, University Hospital Center Zagreb, Zagreb, Croatia Department of Ophthalmology, University Hospital Center Zagreb, Zagreb, Croatia Department of Ophthalmology, University Hospital Center Zagreb, Zagreb, Croatia Department of Ophthalmology, University Hospital Center Zagreb, Zagreb, CroatiaAbstract Purpose: Conventional Descemet's Stripping Automated Endothelial Keratoplasty (DSAEK) is a corneal transplantation procedure where the patient's inner dysfunctional layer is replaced with donor lamella. The data currently present in the literature about the correlation between lamellar thickness and visual acuity is sometimes contradictory and lacks clarity. Methods: Study included 55 eyes that underwent the conventional DSAEK procedure. Patients had no other comorbidities that could affect visual acuity. Data about lamellar thickness and visual acuity were measured six months after surgery with anterior segment optical coherent tomography (A5-OCT). Results: The results show that visual acuity before surgery improved from 0.82 to 0.25 logMAR after surgery. Better visual acuity of 0.20 logMAR was achieved with postoperative lamellas thinner than 124 μm, while statistically significantly lower visual acuity of 0.29 logMAR was gained with postoperative lamellas thicker than 124 μm. Conclusion: Our results suggest that the goal after conventional DSAEK is to have postoperative lamellas thinner than 124 μm in the eye, as this will result in better postoperative visual acuity. This value represents the optimal thickness for conventional DSAEK surgery that could minimize tissue loss for eye banks and surgeons may experience fewer problems during surgery, while obtaining good final visual acuity.https://doi.org/10.18502/jovr.v17i4.12296corneacorneal transplantationdescemet stripping endothelial keratoplastyfuchs's endothelial dystrophy
spellingShingle Tomislav Kuzman
Ana Meter
Miro Kalauz
Sanja Masnec
Ivan Škegro
Ivana Jonjić
Influence of Donor Thickness on Visual Acuity in Descemet’s Stripping Automated Endothelial Keratoplasty
Journal of Ophthalmic & Vision Research
cornea
corneal transplantation
descemet stripping endothelial keratoplasty
fuchs's endothelial dystrophy
title Influence of Donor Thickness on Visual Acuity in Descemet’s Stripping Automated Endothelial Keratoplasty
title_full Influence of Donor Thickness on Visual Acuity in Descemet’s Stripping Automated Endothelial Keratoplasty
title_fullStr Influence of Donor Thickness on Visual Acuity in Descemet’s Stripping Automated Endothelial Keratoplasty
title_full_unstemmed Influence of Donor Thickness on Visual Acuity in Descemet’s Stripping Automated Endothelial Keratoplasty
title_short Influence of Donor Thickness on Visual Acuity in Descemet’s Stripping Automated Endothelial Keratoplasty
title_sort influence of donor thickness on visual acuity in descemet s stripping automated endothelial keratoplasty
topic cornea
corneal transplantation
descemet stripping endothelial keratoplasty
fuchs's endothelial dystrophy
url https://doi.org/10.18502/jovr.v17i4.12296
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