RNA stability is regulated by both RNA polyadenylation and ATP levels, linking RNA and energy metabolisms in Escherichia coli

RNA stability is regulated by both RNA polyadenylation and ATP levels, linking RNA and energy metabolisms in Escherichia coli

ABSTRACT The post-transcriptional process of RNA polyadenylation sits at the crossroads of energy metabolism and RNA metabolism. RNA polyadenylation is catalyzed by poly(A) polymerases, which use ATP as a substrate to add adenine to the 3′ end of RNAs, which can alter their stability. In Escherichia...

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Main Authors: Charlotte Roux, Marvin Ramos-Hue, Marjorie Audonnet, Marie-Pierre Duviau, Sébastien Nouaille, Agamemnon J. Carpousis, Sandrine Laguerre, Eliane Hajnsdorf, Muriel Cocaign-Bousquet, Laurence Girbal
Format: Article
Language:English
Published: American Society for Microbiology 2025-01-01
Series:mBio
Subjects:
RNA polyadenylation
PAP I
RNA stability
energy
ATP
Escherichia coli
Online Access:https://journals.asm.org/doi/10.1128/mbio.02680-24
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