Topical Drug Delivery of Concentrated Cabazitaxel in an α‐Tocopherol and DMSO Solution
Abstract Topical chemotherapy approaches are relevant for certain skin cancer treatments. This study observes that cabazitaxel (CTX), a broad‐spectrum second‐generation taxane cytotoxic agent, can be dissolved in α‐tocopherol at high concentrations exceeding 100 mg mL−1. 2D nuclear magnetic resonanc...
Saved in:
| Main Authors: | Boyang Sun, Georgios Paraskevopoulos, Jiwei Min, Robert Rossdeutcher, Sanjana Ghosh, Breandan Quinn, Meng‐Hsuan Lin, Debanjan Sarkar, Dinesh Sukumaran, Yuefei Wang, Kateřina Vávrová, Jonathan F. Lovell, Yumiao Zhang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2023-10-01
|
| Series: | Advanced Science |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/advs.202302658 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Cetuximab functionalized chitosan/hyaluronic acid-based nanoparticles loaded with cabazitaxel enhances anti-tumor efficacy in DMBA-induced breast cancer model in rats through spatial targeting
by: Abhishek Jha, et al.
Published: (2024-12-01) -
Association between the apoptotic effect of Cabazitaxel and its pro-oxidant efficacy on the redox adaptation mechanisms in prostate cancer cells with different resistance phenotypes
by: Isil Ezgi Eryilmaz, et al.
Published: (2024-12-01) -
Stability and Reactivity of Tocopherols: Theoretical Study
by: Nasséra Benbrahim, et al.
Published: (2023-11-01) -
Anticancer Potential of Tocopherols-Containing Plants and Semi-Synthetic Tocopherols
by: Nesti Fronika Sianipar, et al.
Published: (2024-10-01) -
The changes of Trp-deficient linusorb during the oxidation and the influence of γ-tocopherol on their oxidative stability
by: Dujian Deng, et al.
Published: (2024-12-01)