The predictive value of the ARC-HBR criteria for in-hospital bleeding risk following percutaneous coronary intervention in patients with acute coronary syndrome
Background: The Academic Research Consortium for High Bleeding Risk (ARC-HBR) criteria were proposed for predicting bleeding risk in patients undergoing percutaneous coronary intervention (PCI). However, there is a lack of research evaluating the risk of in-hospital bleeding following PCI for acute...
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Elsevier
2024-12-01
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| Series: | International Journal of Cardiology: Heart & Vasculature |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352906724001933 |
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| author | Juan Liu Hui He Hong Su Jun Hou Yan Luo Qiang Chen Qiao Feng Xiufen Peng Maoling Jiang Long Xia Hanxiong Liu Zhen Zhang Shiqiang Xiong Lin Cai |
| author_facet | Juan Liu Hui He Hong Su Jun Hou Yan Luo Qiang Chen Qiao Feng Xiufen Peng Maoling Jiang Long Xia Hanxiong Liu Zhen Zhang Shiqiang Xiong Lin Cai |
| author_sort | Juan Liu |
| collection | DOAJ |
| description | Background: The Academic Research Consortium for High Bleeding Risk (ARC-HBR) criteria were proposed for predicting bleeding risk in patients undergoing percutaneous coronary intervention (PCI). However, there is a lack of research evaluating the risk of in-hospital bleeding following PCI for acute coronary syndrome (ACS) utilizing the ARC-HBR criteria. Methods and results: This study involved 1013 ACS patients who underwent PCI and dual antiplatelet therapy. There were 63 cases of in-hospital bleeding events (6.22 %). According to the ARC-HBR criteria, patients classified as HBR had a significantly greater bleeding rate than non-HBR patients (15.81 % vs. 1.99 %, p < 0.001). As the CRUSADE score category increased, the risk of bleeding also increased. The area under the receiver operating characteristic curve (AUC) of the ARC-HBR criteria was significantly greater than that of the CRUSADE score for bleeding (0.751 vs. 0.696, p < 0.0001). Subgroup analysis revealed that the ARC-HBR criteria exhibited better predictive ability for ST-segment elevation myocardial infarction (STEMI, AUC 0.767 vs. 0.694, p = 0.020) but comparable predictive ability in patients with unstable angina (AUC 0.756 vs. 0.644, p = 0.213), non-ST-segment elevation myocardial infarction (AUC 0.713 vs. 0.683, p = 0.644), and non-ST-segment elevation ACS (AUC 0.739 vs. 0.687, p = 0.330). Conclusion: Compared with the CRUSADE score, the ARC-HBR criteria demonstrate superior predictive ability for in-hospital bleeding events during PCI in ACS patients. Routine assessment of the ARC-HBR score might be helpful for identifying high-risk individuals in this specific population. |
| format | Article |
| id | doaj-art-a8227fa868784701892555ec6f2634e7 |
| institution | Kabale University |
| issn | 2352-9067 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | International Journal of Cardiology: Heart & Vasculature |
| spelling | doaj-art-a8227fa868784701892555ec6f2634e72024-11-29T06:24:22ZengElsevierInternational Journal of Cardiology: Heart & Vasculature2352-90672024-12-0155101527The predictive value of the ARC-HBR criteria for in-hospital bleeding risk following percutaneous coronary intervention in patients with acute coronary syndromeJuan Liu0Hui He1Hong Su2Jun Hou3Yan Luo4Qiang Chen5Qiao Feng6Xiufen Peng7Maoling Jiang8Long Xia9Hanxiong Liu10Zhen Zhang11Shiqiang Xiong12Lin Cai13Department of Cardiology, Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan, China; Department of Cardiology, Anzhou District People’s Hospital, Mianyang, Sichuan, ChinaDepartment of Cardiology, Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan, China; Department of Intensive Care Unit, Jinniu District People’s Hospital, Jinniu Hospital of Sichuan Provincial People’s Hospital, Chengdu, Sichuan, ChinaDepartment of Cardiology, The Third People’s Hospital of Chengdu, Affiliated Hospital of Southwest Jiaotong University, Chengdu Cardiovascular Disease Research Institute, Chengdu, Sichuan, China; Department of Cardiology, Integrated Traditional Chinese and Western Medicine Hospital of Panzhihua, The Affliated Hospital of Panzhihua Medical College, Panzhihua, Sichuan, ChinaDepartment of Cardiology, The Third People’s Hospital of Chengdu, Affiliated Hospital of Southwest Jiaotong University, Chengdu Cardiovascular Disease Research Institute, Chengdu, Sichuan, ChinaDepartment of Cardiology, The Third People’s Hospital of Chengdu, Affiliated Hospital of Southwest Jiaotong University, Chengdu Cardiovascular Disease Research Institute, Chengdu, Sichuan, ChinaDepartment of Cardiology, The Third People’s Hospital of Chengdu, Affiliated Hospital of Southwest Jiaotong University, Chengdu Cardiovascular Disease Research Institute, Chengdu, Sichuan, ChinaDepartment of Cardiology, The Third People’s Hospital of Chengdu, Affiliated Hospital of Southwest Jiaotong University, Chengdu Cardiovascular Disease Research Institute, Chengdu, Sichuan, ChinaDepartment of Cardiology, The Third People’s Hospital of Chengdu, Affiliated Hospital of Southwest Jiaotong University, Chengdu Cardiovascular Disease Research Institute, Chengdu, Sichuan, ChinaDepartment of Cardiology, The Third People’s Hospital of Chengdu, Affiliated Hospital of Southwest Jiaotong University, Chengdu Cardiovascular Disease Research Institute, Chengdu, Sichuan, ChinaDepartment of Cardiology, The Third People’s Hospital of Chengdu, Affiliated Hospital of Southwest Jiaotong University, Chengdu Cardiovascular Disease Research Institute, Chengdu, Sichuan, ChinaDepartment of Cardiology, The Third People’s Hospital of Chengdu, Affiliated Hospital of Southwest Jiaotong University, Chengdu Cardiovascular Disease Research Institute, Chengdu, Sichuan, ChinaDepartment of Cardiology, The Third People’s Hospital of Chengdu, Affiliated Hospital of Southwest Jiaotong University, Chengdu Cardiovascular Disease Research Institute, Chengdu, Sichuan, China; Corresponding authors.Department of Cardiology, The Third People’s Hospital of Chengdu, Affiliated Hospital of Southwest Jiaotong University, Chengdu Cardiovascular Disease Research Institute, Chengdu, Sichuan, China; Corresponding authors.Department of Cardiology, Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan, China; Department of Cardiology, The Third People’s Hospital of Chengdu, Affiliated Hospital of Southwest Jiaotong University, Chengdu Cardiovascular Disease Research Institute, Chengdu, Sichuan, China; Corresponding authors.Background: The Academic Research Consortium for High Bleeding Risk (ARC-HBR) criteria were proposed for predicting bleeding risk in patients undergoing percutaneous coronary intervention (PCI). However, there is a lack of research evaluating the risk of in-hospital bleeding following PCI for acute coronary syndrome (ACS) utilizing the ARC-HBR criteria. Methods and results: This study involved 1013 ACS patients who underwent PCI and dual antiplatelet therapy. There were 63 cases of in-hospital bleeding events (6.22 %). According to the ARC-HBR criteria, patients classified as HBR had a significantly greater bleeding rate than non-HBR patients (15.81 % vs. 1.99 %, p < 0.001). As the CRUSADE score category increased, the risk of bleeding also increased. The area under the receiver operating characteristic curve (AUC) of the ARC-HBR criteria was significantly greater than that of the CRUSADE score for bleeding (0.751 vs. 0.696, p < 0.0001). Subgroup analysis revealed that the ARC-HBR criteria exhibited better predictive ability for ST-segment elevation myocardial infarction (STEMI, AUC 0.767 vs. 0.694, p = 0.020) but comparable predictive ability in patients with unstable angina (AUC 0.756 vs. 0.644, p = 0.213), non-ST-segment elevation myocardial infarction (AUC 0.713 vs. 0.683, p = 0.644), and non-ST-segment elevation ACS (AUC 0.739 vs. 0.687, p = 0.330). Conclusion: Compared with the CRUSADE score, the ARC-HBR criteria demonstrate superior predictive ability for in-hospital bleeding events during PCI in ACS patients. Routine assessment of the ARC-HBR score might be helpful for identifying high-risk individuals in this specific population.http://www.sciencedirect.com/science/article/pii/S2352906724001933High bleeding riskARC-HBR criteriaCRUSADE scorePercutaneous coronary intervention |
| spellingShingle | Juan Liu Hui He Hong Su Jun Hou Yan Luo Qiang Chen Qiao Feng Xiufen Peng Maoling Jiang Long Xia Hanxiong Liu Zhen Zhang Shiqiang Xiong Lin Cai The predictive value of the ARC-HBR criteria for in-hospital bleeding risk following percutaneous coronary intervention in patients with acute coronary syndrome International Journal of Cardiology: Heart & Vasculature High bleeding risk ARC-HBR criteria CRUSADE score Percutaneous coronary intervention |
| title | The predictive value of the ARC-HBR criteria for in-hospital bleeding risk following percutaneous coronary intervention in patients with acute coronary syndrome |
| title_full | The predictive value of the ARC-HBR criteria for in-hospital bleeding risk following percutaneous coronary intervention in patients with acute coronary syndrome |
| title_fullStr | The predictive value of the ARC-HBR criteria for in-hospital bleeding risk following percutaneous coronary intervention in patients with acute coronary syndrome |
| title_full_unstemmed | The predictive value of the ARC-HBR criteria for in-hospital bleeding risk following percutaneous coronary intervention in patients with acute coronary syndrome |
| title_short | The predictive value of the ARC-HBR criteria for in-hospital bleeding risk following percutaneous coronary intervention in patients with acute coronary syndrome |
| title_sort | predictive value of the arc hbr criteria for in hospital bleeding risk following percutaneous coronary intervention in patients with acute coronary syndrome |
| topic | High bleeding risk ARC-HBR criteria CRUSADE score Percutaneous coronary intervention |
| url | http://www.sciencedirect.com/science/article/pii/S2352906724001933 |
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