The clinical value of Delphian and pre-tracheal lymph nodes in predicting lateral lymph nodes metastasis of papillary thyroid carcinoma
Background Occult lymph node metastasis of papillary thyroid carcinoma is common. However, whether undergoing prophylactic lateral lymph node dissections is still controversial. This cross-sectional study with large cohort of patients aims to investigate the clinical value of Delphian and pre-trache...
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Taylor & Francis Group
2025-12-01
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| Series: | Annals of Medicine |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/07853890.2024.2444551 |
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| author | Chun Huang Jing Zhou Yuchen Zhuang Tao Xu Xinliang Su |
| author_facet | Chun Huang Jing Zhou Yuchen Zhuang Tao Xu Xinliang Su |
| author_sort | Chun Huang |
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| description | Background Occult lymph node metastasis of papillary thyroid carcinoma is common. However, whether undergoing prophylactic lateral lymph node dissections is still controversial. This cross-sectional study with large cohort of patients aims to investigate the clinical value of Delphian and pre-tracheal lymph node in predicting lateral lymph node metastasis of papillary thyroid carcinoma.Materials and methods A retrospective analysis was conducted on 865 papillary thyroid carcinoma patients with Delphian and pre-tracheal lymph node data who underwent thyroidectomy plus central and lateral lymph node dissection. Data on clinicopathological characteristics were collected. Subsequently, a predictive model was established based on the results of the univariate and multivariate analyses.Results The rates of Delphian and pre-tracheal lymph node metastasis and lateral lymph node metastasis were 54.7% and 39.1%, respectively. Having ≥ 3 or 1–2 Delphian and pre-tracheal lymph node metastasis dramatically increased the risk of lateral lymph node metastasis (OR = 8.5, 95% CI 5.3–13.4 and OR = 3.9, 95% CI 2.7–5.7, respectively). The upper tumour had a 3.7 times higher risk of lateral lymph node metastasis than other locations. Patients ≤ 42 years or tumour size >8 mm had a higher risk of lateral lymph node metastasis.Conclusions Delphian and pre-tracheal lymph node metastasis was associated positively with the risk of lateral lymph node metastasis. For patients without clinical lateral lymph node metastasis, the Delphian and pre-tracheal lymph node could be considered to harvest as the first step in a thyroidectomy to facilitate further conduct of the operation. |
| format | Article |
| id | doaj-art-a820c69b423a4fa3b354a19050e1a9a5 |
| institution | Kabale University |
| issn | 0785-3890 1365-2060 |
| language | English |
| publishDate | 2025-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Annals of Medicine |
| spelling | doaj-art-a820c69b423a4fa3b354a19050e1a9a52024-12-20T14:53:49ZengTaylor & Francis GroupAnnals of Medicine0785-38901365-20602025-12-0157110.1080/07853890.2024.2444551The clinical value of Delphian and pre-tracheal lymph nodes in predicting lateral lymph nodes metastasis of papillary thyroid carcinomaChun Huang0Jing Zhou1Yuchen Zhuang2Tao Xu3Xinliang Su4Department of Breast and Thyroid Surgery, the First Affiliated Hospital of Chongqing Medical University, Chongqing, ChinaDepartment of Breast and Thyroid Surgery, Chongqing Health Center for Women and Children Women and Children’s Hospital of Chongqing Medical University, Chongqing, ChinaDepartment of Breast and Thyroid Surgery, Chongqing Health Center for Women and Children Women and Children’s Hospital of Chongqing Medical University, Chongqing, ChinaDepartment of Breast and Thyroid Surgery, the First Affiliated Hospital of Chongqing Medical University, Chongqing, ChinaDepartment of Breast and Thyroid Surgery, the First Affiliated Hospital of Chongqing Medical University, Chongqing, ChinaBackground Occult lymph node metastasis of papillary thyroid carcinoma is common. However, whether undergoing prophylactic lateral lymph node dissections is still controversial. This cross-sectional study with large cohort of patients aims to investigate the clinical value of Delphian and pre-tracheal lymph node in predicting lateral lymph node metastasis of papillary thyroid carcinoma.Materials and methods A retrospective analysis was conducted on 865 papillary thyroid carcinoma patients with Delphian and pre-tracheal lymph node data who underwent thyroidectomy plus central and lateral lymph node dissection. Data on clinicopathological characteristics were collected. Subsequently, a predictive model was established based on the results of the univariate and multivariate analyses.Results The rates of Delphian and pre-tracheal lymph node metastasis and lateral lymph node metastasis were 54.7% and 39.1%, respectively. Having ≥ 3 or 1–2 Delphian and pre-tracheal lymph node metastasis dramatically increased the risk of lateral lymph node metastasis (OR = 8.5, 95% CI 5.3–13.4 and OR = 3.9, 95% CI 2.7–5.7, respectively). The upper tumour had a 3.7 times higher risk of lateral lymph node metastasis than other locations. Patients ≤ 42 years or tumour size >8 mm had a higher risk of lateral lymph node metastasis.Conclusions Delphian and pre-tracheal lymph node metastasis was associated positively with the risk of lateral lymph node metastasis. For patients without clinical lateral lymph node metastasis, the Delphian and pre-tracheal lymph node could be considered to harvest as the first step in a thyroidectomy to facilitate further conduct of the operation.https://www.tandfonline.com/doi/10.1080/07853890.2024.2444551Delphian and pre-tracheal lymph nodepapillary thyroid carcinomalateral lymph node metastasislymph node dissection |
| spellingShingle | Chun Huang Jing Zhou Yuchen Zhuang Tao Xu Xinliang Su The clinical value of Delphian and pre-tracheal lymph nodes in predicting lateral lymph nodes metastasis of papillary thyroid carcinoma Annals of Medicine Delphian and pre-tracheal lymph node papillary thyroid carcinoma lateral lymph node metastasis lymph node dissection |
| title | The clinical value of Delphian and pre-tracheal lymph nodes in predicting lateral lymph nodes metastasis of papillary thyroid carcinoma |
| title_full | The clinical value of Delphian and pre-tracheal lymph nodes in predicting lateral lymph nodes metastasis of papillary thyroid carcinoma |
| title_fullStr | The clinical value of Delphian and pre-tracheal lymph nodes in predicting lateral lymph nodes metastasis of papillary thyroid carcinoma |
| title_full_unstemmed | The clinical value of Delphian and pre-tracheal lymph nodes in predicting lateral lymph nodes metastasis of papillary thyroid carcinoma |
| title_short | The clinical value of Delphian and pre-tracheal lymph nodes in predicting lateral lymph nodes metastasis of papillary thyroid carcinoma |
| title_sort | clinical value of delphian and pre tracheal lymph nodes in predicting lateral lymph nodes metastasis of papillary thyroid carcinoma |
| topic | Delphian and pre-tracheal lymph node papillary thyroid carcinoma lateral lymph node metastasis lymph node dissection |
| url | https://www.tandfonline.com/doi/10.1080/07853890.2024.2444551 |
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