Multidrug-resistant Klebsiella pneumoniae ST70 harboring bla NDM in a migratory Penguin
Abstract The growing prevalence of antimicrobial resistance poses a global threat to human and animal health. In this study, we investigated the occurrence and genetic basis of antimicrobial resistance in a Magellanic Penguin (Spheniscus magellanicus) rescued off the coast of Rio de Janeiro, Brazil....
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2025-07-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-025-97816-4 |
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| author | Sandryelle Merces Freire Annelise Kyllar Marina Côrtes Thiago P. G. Chagas Felipe Pinheiro Renata F. A. Pereira Fabio Aguiar-Alves Bruno Penna |
| author_facet | Sandryelle Merces Freire Annelise Kyllar Marina Côrtes Thiago P. G. Chagas Felipe Pinheiro Renata F. A. Pereira Fabio Aguiar-Alves Bruno Penna |
| author_sort | Sandryelle Merces Freire |
| collection | DOAJ |
| description | Abstract The growing prevalence of antimicrobial resistance poses a global threat to human and animal health. In this study, we investigated the occurrence and genetic basis of antimicrobial resistance in a Magellanic Penguin (Spheniscus magellanicus) rescued off the coast of Rio de Janeiro, Brazil. The penguin presented a bacterial infection, identified as Klebsiella pneumoniae. Molecular analysis revealed the presence of several resistance genes, including those that confer resistance to carbapenems, beta-lactams, quinolones, and other classes of antibiotics. The bacterial strain belonged to Sequence Type 70 (ST70), a clone previously associated with human nosocomial infections. This study highlights the potential of migratory penguins as vectors of antimicrobial-resistant microorganisms, emphasizing the need for a One Health approach to address the complex interaction between environmental factors, animal health, and human well-being. The findings underscore the urgency of implementing strategies to mitigate the spread of multidrug-resistant bacteria in natural and urban environments. |
| format | Article |
| id | doaj-art-a80f370f532f4dbaa59f1987fdc8565b |
| institution | Kabale University |
| issn | 2045-2322 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj-art-a80f370f532f4dbaa59f1987fdc8565b2025-08-20T04:01:35ZengNature PortfolioScientific Reports2045-23222025-07-011511710.1038/s41598-025-97816-4Multidrug-resistant Klebsiella pneumoniae ST70 harboring bla NDM in a migratory PenguinSandryelle Merces Freire0Annelise Kyllar1Marina Côrtes2Thiago P. G. Chagas3Felipe Pinheiro4Renata F. A. Pereira5Fabio Aguiar-Alves6Bruno Penna7Laboratório de Cocos Gram Positivos do Instituto Biomédico, Universidade Federal FluminenseLaboratório de Cocos Gram Positivos do Instituto Biomédico, Universidade Federal FluminenseInstituto de Medicina Tropical da Faculdade de Medicina, Universidade de São PauloMolecular Epidemiology and Biotechnology Laboratory, Faculty of Pharmacy, Universidade Federal FluminenseMolecular Epidemiology and Biotechnology Laboratory, Faculty of Pharmacy, Universidade Federal FluminenseMolecular Epidemiology and Biotechnology Laboratory, Faculty of Pharmacy, Universidade Federal FluminensePharmaceutical Sciences, Lloyd L. Gregory School of Pharmacy, Palm Beach Atlantic UniversityLaboratório de Cocos Gram Positivos do Instituto Biomédico, Universidade Federal FluminenseAbstract The growing prevalence of antimicrobial resistance poses a global threat to human and animal health. In this study, we investigated the occurrence and genetic basis of antimicrobial resistance in a Magellanic Penguin (Spheniscus magellanicus) rescued off the coast of Rio de Janeiro, Brazil. The penguin presented a bacterial infection, identified as Klebsiella pneumoniae. Molecular analysis revealed the presence of several resistance genes, including those that confer resistance to carbapenems, beta-lactams, quinolones, and other classes of antibiotics. The bacterial strain belonged to Sequence Type 70 (ST70), a clone previously associated with human nosocomial infections. This study highlights the potential of migratory penguins as vectors of antimicrobial-resistant microorganisms, emphasizing the need for a One Health approach to address the complex interaction between environmental factors, animal health, and human well-being. The findings underscore the urgency of implementing strategies to mitigate the spread of multidrug-resistant bacteria in natural and urban environments.https://doi.org/10.1038/s41598-025-97816-4 |
| spellingShingle | Sandryelle Merces Freire Annelise Kyllar Marina Côrtes Thiago P. G. Chagas Felipe Pinheiro Renata F. A. Pereira Fabio Aguiar-Alves Bruno Penna Multidrug-resistant Klebsiella pneumoniae ST70 harboring bla NDM in a migratory Penguin Scientific Reports |
| title | Multidrug-resistant Klebsiella pneumoniae ST70 harboring bla NDM in a migratory Penguin |
| title_full | Multidrug-resistant Klebsiella pneumoniae ST70 harboring bla NDM in a migratory Penguin |
| title_fullStr | Multidrug-resistant Klebsiella pneumoniae ST70 harboring bla NDM in a migratory Penguin |
| title_full_unstemmed | Multidrug-resistant Klebsiella pneumoniae ST70 harboring bla NDM in a migratory Penguin |
| title_short | Multidrug-resistant Klebsiella pneumoniae ST70 harboring bla NDM in a migratory Penguin |
| title_sort | multidrug resistant klebsiella pneumoniae st70 harboring bla ndm in a migratory penguin |
| url | https://doi.org/10.1038/s41598-025-97816-4 |
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