Bridged emulsion gels from polymer–nanoparticle enabling large-amount biomedical encapsulation and functionalization
Abstract Large-amount encapsulation and subsequent expressing are common characteristics for many biomedical applications, such as cosmetic creams and medical ointments. Emulsion gels can accomplish that, but often undergo exclusive, complex, multiple synthesis steps, showing extremely laborious and...
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Nature Portfolio
2024-12-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-024-55099-9 |
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| author | Chuchu Wan Si He Quanyong Cheng Kehan Du Yuhang Song Xiang Yu Hao Jiang Caili Huang Jiangping Xu Cong Ma Jintao Zhu |
| author_facet | Chuchu Wan Si He Quanyong Cheng Kehan Du Yuhang Song Xiang Yu Hao Jiang Caili Huang Jiangping Xu Cong Ma Jintao Zhu |
| author_sort | Chuchu Wan |
| collection | DOAJ |
| description | Abstract Large-amount encapsulation and subsequent expressing are common characteristics for many biomedical applications, such as cosmetic creams and medical ointments. Emulsion gels can accomplish that, but often undergo exclusive, complex, multiple synthesis steps, showing extremely laborious and non-universal. The method here is simple via precisely interfacial engineering in homogenizing a nanoparticle aqueous dispersion and a polymer oil solution, gaining interfacial 45° three-phase-contact-angle for the nanoparticle that can bridge across oil emulsions’ interfaces and ultimately form interconnected macroscopic networks. Their bridged skeletons and rheology are tunable over a vast range and deterministic on the basis of components’ inputs. Furthermore, emulsion gels with high encapsulation and storage ability encapsulating active sunscreen ingredients, as a proof-of-concept, outperform commercial products. The ease (only seconds by strongly mixing two solutions) and the versatile chemical selection of our synthetic emulsion gels suggest an exciting general, scalable strategy for the next-generation cosmetic, ointment or otherwise food gel systems. |
| format | Article |
| id | doaj-art-a8015bb0a3d74e7a9680bf7271dce760 |
| institution | Kabale University |
| issn | 2041-1723 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj-art-a8015bb0a3d74e7a9680bf7271dce7602025-01-05T12:36:00ZengNature PortfolioNature Communications2041-17232024-12-0115111210.1038/s41467-024-55099-9Bridged emulsion gels from polymer–nanoparticle enabling large-amount biomedical encapsulation and functionalizationChuchu Wan0Si He1Quanyong Cheng2Kehan Du3Yuhang Song4Xiang Yu5Hao Jiang6Caili Huang7Jiangping Xu8Cong Ma9Jintao Zhu10Key Laboratory of Materials Chemistry for Energy Conversion and Storage of Ministry of Education (HUST), School of Chemistry and Chemical Engineering, Huazhong University of Science and Technology (HUST)Key Laboratory of Molecular Biophysics of the Ministry of Education (HUST), College of Life Science and Technology, Huazhong University of Science and Technology (HUST)Key Laboratory of Materials Chemistry for Energy Conversion and Storage of Ministry of Education (HUST), School of Chemistry and Chemical Engineering, Huazhong University of Science and Technology (HUST)Key Laboratory of Materials Chemistry for Energy Conversion and Storage of Ministry of Education (HUST), School of Chemistry and Chemical Engineering, Huazhong University of Science and Technology (HUST)Key Laboratory of Materials Chemistry for Energy Conversion and Storage of Ministry of Education (HUST), School of Chemistry and Chemical Engineering, Huazhong University of Science and Technology (HUST)Key Laboratory of Materials Chemistry for Energy Conversion and Storage of Ministry of Education (HUST), School of Chemistry and Chemical Engineering, Huazhong University of Science and Technology (HUST)Key Laboratory of Materials Chemistry for Energy Conversion and Storage of Ministry of Education (HUST), School of Chemistry and Chemical Engineering, Huazhong University of Science and Technology (HUST)Key Laboratory of Materials Chemistry for Energy Conversion and Storage of Ministry of Education (HUST), School of Chemistry and Chemical Engineering, Huazhong University of Science and Technology (HUST)Key Laboratory of Materials Chemistry for Energy Conversion and Storage of Ministry of Education (HUST), School of Chemistry and Chemical Engineering, Huazhong University of Science and Technology (HUST)Key Laboratory of Molecular Biophysics of the Ministry of Education (HUST), College of Life Science and Technology, Huazhong University of Science and Technology (HUST)Key Laboratory of Materials Chemistry for Energy Conversion and Storage of Ministry of Education (HUST), School of Chemistry and Chemical Engineering, Huazhong University of Science and Technology (HUST)Abstract Large-amount encapsulation and subsequent expressing are common characteristics for many biomedical applications, such as cosmetic creams and medical ointments. Emulsion gels can accomplish that, but often undergo exclusive, complex, multiple synthesis steps, showing extremely laborious and non-universal. The method here is simple via precisely interfacial engineering in homogenizing a nanoparticle aqueous dispersion and a polymer oil solution, gaining interfacial 45° three-phase-contact-angle for the nanoparticle that can bridge across oil emulsions’ interfaces and ultimately form interconnected macroscopic networks. Their bridged skeletons and rheology are tunable over a vast range and deterministic on the basis of components’ inputs. Furthermore, emulsion gels with high encapsulation and storage ability encapsulating active sunscreen ingredients, as a proof-of-concept, outperform commercial products. The ease (only seconds by strongly mixing two solutions) and the versatile chemical selection of our synthetic emulsion gels suggest an exciting general, scalable strategy for the next-generation cosmetic, ointment or otherwise food gel systems.https://doi.org/10.1038/s41467-024-55099-9 |
| spellingShingle | Chuchu Wan Si He Quanyong Cheng Kehan Du Yuhang Song Xiang Yu Hao Jiang Caili Huang Jiangping Xu Cong Ma Jintao Zhu Bridged emulsion gels from polymer–nanoparticle enabling large-amount biomedical encapsulation and functionalization Nature Communications |
| title | Bridged emulsion gels from polymer–nanoparticle enabling large-amount biomedical encapsulation and functionalization |
| title_full | Bridged emulsion gels from polymer–nanoparticle enabling large-amount biomedical encapsulation and functionalization |
| title_fullStr | Bridged emulsion gels from polymer–nanoparticle enabling large-amount biomedical encapsulation and functionalization |
| title_full_unstemmed | Bridged emulsion gels from polymer–nanoparticle enabling large-amount biomedical encapsulation and functionalization |
| title_short | Bridged emulsion gels from polymer–nanoparticle enabling large-amount biomedical encapsulation and functionalization |
| title_sort | bridged emulsion gels from polymer nanoparticle enabling large amount biomedical encapsulation and functionalization |
| url | https://doi.org/10.1038/s41467-024-55099-9 |
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