Parvoviruses NS1 oncolytic attributes: mechanistic insights and synergistic anti-tumor therapeutic strategies

Parvoviruses NS1 oncolytic attributes: mechanistic insights and synergistic anti-tumor therapeutic strategies

Parvovirus is comprised of a single-stranded DNA structure, encompassing distinct structural and non-structural proteins. Structural proteins are referred as viral proteins, which facilitate for the viral capsid. Among non-structural proteins, NS1 is the most significant, exhibiting substantial char...

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Bibliographic Details
Main Authors: Abdul Haseeb, Wafa Yousaf, Zhigang Cao, Kuohai Fan, Na Sun, Panpan Sun, Yaogui Sun, Huizhen Yang, Wei Yin, Hua Zhang, Zhenbiao Zhang, Jia Zhong, Jianzhong Wang, Hongquan Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Microbiology
Subjects:
parvoviruses
NS1
cell cycle arrest
apoptosis
oncolysis
immunomodulation
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1631433/full
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https://www.frontiersin.org/articles/10.3389/fmicb.2025.1631433/full

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