Deep genome sequencing reveals extensive genetic heterogeneity in early human placentas

Deep genome sequencing reveals extensive genetic heterogeneity in early human placentas

Abstract Placental biopsy in early pregnancy is widely used in prenatal genetic diagnostics as a surrogate for fetal tissue. Confined placental chromosomal mosaicism is a well-documented phenomenon causing genetic discrepancies between the fetus and placenta. Although comprehensive sequencing method...

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Bibliographic Details
Main Authors: Ieva Miceikaite, Christina Fagerberg, Charlotte Brasch-Andersen, Pernille M. Torring, Britta Schlott Kristiansen, Qin Hao, Lene Sperling, Martin J. Larsen
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-63296-3
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