The anticarcinogenic properties of manuka honey - a literature review
Background: Since antiquity, honey has been recognised for its healing and antibacterial properties. Recently, Manuka honey (MH) has been identified as possessing antioxidant, anti-inflammatory, antimutagenic, and anticarcinogenic effects. Objective: This review examines the potential benefits o...
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| Format: | Article |
| Language: | English |
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Nicolaus Copernicus University in Toruń
2024-12-01
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| Series: | Quality in Sport |
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| Online Access: | https://apcz.umk.pl/QS/article/view/56542 |
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| author | Adrianna Muciek Martyna Mocarska Anna Orłowska Katarzyna Strakowska Laura Opalska Anna Maryńczak Jan Mencel Nicole Nitschke |
| author_facet | Adrianna Muciek Martyna Mocarska Anna Orłowska Katarzyna Strakowska Laura Opalska Anna Maryńczak Jan Mencel Nicole Nitschke |
| author_sort | Adrianna Muciek |
| collection | DOAJ |
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Background: Since antiquity, honey has been recognised for its healing and antibacterial properties. Recently, Manuka honey (MH) has been identified as possessing antioxidant, anti-inflammatory, antimutagenic, and anticarcinogenic effects.
Objective: This review examines the potential benefits of manuka honey, its bioactive components, and their effects on cancerogenesis, cancer growth, and development.
Methods: The PubMed and Google Scholar databases were searched, and 46 studies were identified as most relevant to the research objective.
Results: The accompanying papers posit that MH may impede carcinogenesis by regulating various molecular pathways and cancer cell progression. A substantial body of scientific evidence indicates that a range of honey types, including MH, can facilitate the release of reactive oxygen species and cytokines (predominantly IL-1β, IL-6, and TNF-α) by innate immune system cells. Furthermore, studies have demonstrated that honey can stimulate T lymphocytes and macrophages' proliferation and functions while also inducing apoptosis and cell cycle arrest in cancer cells.
Conclusion: The body of evidence attesting to the anticarcinogenic properties of MH continues to grow. Several studies have demonstrated the significant role of manuka honey and its properties in promoting innate and adaptive immunity, which is essential for eliminating cancer cells. Nevertheless, further research is required to provide comprehensive data regarding the active constituents of Manuka honey and their potential efficacy in cancer therapy.
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| format | Article |
| id | doaj-art-a78e7a842c684e74be990d805642c9b0 |
| institution | Kabale University |
| issn | 2450-3118 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Nicolaus Copernicus University in Toruń |
| record_format | Article |
| series | Quality in Sport |
| spelling | doaj-art-a78e7a842c684e74be990d805642c9b02024-12-29T08:22:19ZengNicolaus Copernicus University in ToruńQuality in Sport2450-31182024-12-012510.12775/QS.2024.25.56542The anticarcinogenic properties of manuka honey - a literature reviewAdrianna Muciek0https://orcid.org/0009-0002-5678-3780Martyna Mocarska1https://orcid.org/0009-0007-4249-9857Anna Orłowska2https://orcid.org/0009-0000-6028-3004Katarzyna Strakowska3https://orcid.org/0009-0006-6202-2055Laura Opalska4https://orcid.org/0009-0007-3122-3484Anna Maryńczak5https://orcid.org/0000-0001-6187-0921Jan Mencel6https://orcid.org/0009-0006-0877-2242Nicole Nitschke7https://orcid.org/0009-0003-9817-7903The University Hospital in Krakow, Jakubowskiego 2 Street, 30-688 Krakow: Cracow, Malopolska, PLGabriel Narutowicz Municipal Specialist Hospital, Prądnicka 35 Street, 31-202 Kraków: Cracow, Malopolska, PLThe University Hospital in Krakow, Jakubowskiego 2 Street, 30-688 Krakow: Cracow, Malopolska, PLThe Ludwik Rydygier Memorial Specialized Hospital, Osiedle Złotej Jesieni 1, 31-820 Krakow: Cracow, Malopolska, PLThe University Hospital in Krakow, Jakubowskiego 2 Street, 30-688 Krakow: Cracow, Malopolska, PLClinical Provincial Hospital No. 2 them. Saint Jadwiga the Queen in Rzeszów, Lwowska 60 Street, 35-301 Rzeszów, Subcarpathia, PLIndependent Public Health Care Facility of the Ministry of Internal Affairs and Administration in Krakow, Kronikarza Galla 25 Street, 30-053 Krakow: Cracow, Malopolska, PLThe University Hospital in Krakow, Jakubowskiego 2 Street, 30-688 Krakow: Cracow, Malopolska, PL Background: Since antiquity, honey has been recognised for its healing and antibacterial properties. Recently, Manuka honey (MH) has been identified as possessing antioxidant, anti-inflammatory, antimutagenic, and anticarcinogenic effects. Objective: This review examines the potential benefits of manuka honey, its bioactive components, and their effects on cancerogenesis, cancer growth, and development. Methods: The PubMed and Google Scholar databases were searched, and 46 studies were identified as most relevant to the research objective. Results: The accompanying papers posit that MH may impede carcinogenesis by regulating various molecular pathways and cancer cell progression. A substantial body of scientific evidence indicates that a range of honey types, including MH, can facilitate the release of reactive oxygen species and cytokines (predominantly IL-1β, IL-6, and TNF-α) by innate immune system cells. Furthermore, studies have demonstrated that honey can stimulate T lymphocytes and macrophages' proliferation and functions while also inducing apoptosis and cell cycle arrest in cancer cells. Conclusion: The body of evidence attesting to the anticarcinogenic properties of MH continues to grow. Several studies have demonstrated the significant role of manuka honey and its properties in promoting innate and adaptive immunity, which is essential for eliminating cancer cells. Nevertheless, further research is required to provide comprehensive data regarding the active constituents of Manuka honey and their potential efficacy in cancer therapy. https://apcz.umk.pl/QS/article/view/56542Manuka honeyLeptospermum scopariumcanceranticarcinogenic |
| spellingShingle | Adrianna Muciek Martyna Mocarska Anna Orłowska Katarzyna Strakowska Laura Opalska Anna Maryńczak Jan Mencel Nicole Nitschke The anticarcinogenic properties of manuka honey - a literature review Quality in Sport Manuka honey Leptospermum scoparium cancer anticarcinogenic |
| title | The anticarcinogenic properties of manuka honey - a literature review |
| title_full | The anticarcinogenic properties of manuka honey - a literature review |
| title_fullStr | The anticarcinogenic properties of manuka honey - a literature review |
| title_full_unstemmed | The anticarcinogenic properties of manuka honey - a literature review |
| title_short | The anticarcinogenic properties of manuka honey - a literature review |
| title_sort | anticarcinogenic properties of manuka honey a literature review |
| topic | Manuka honey Leptospermum scoparium cancer anticarcinogenic |
| url | https://apcz.umk.pl/QS/article/view/56542 |
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