Evaluation of Delirium Risk Factors in Intensive Care Patients

Objective: The negative effects of delirium in intensive care unit (ICU) patients necessitate the identification and management of risk factors. This study aimed to determine the incidence of delirium and its associated modifiable and non-modifiable factors in the ICU setting to provide valuable ins...

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Main Authors: Selin Erel, Eda Macit Aydın, Bijen Nazlıel, Lale Karabıyık
Format: Article
Language:English
Published: Galenos Publishing House 2024-12-01
Series:Turkish Journal of Anaesthesiology and Reanimation
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Online Access:https://turkjanaesthesiolreanim.org/articles/evaluation-of-delirium-risk-factors-in-intensive-care-patients/doi/TJAR.2024.241526
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author Selin Erel
Eda Macit Aydın
Bijen Nazlıel
Lale Karabıyık
author_facet Selin Erel
Eda Macit Aydın
Bijen Nazlıel
Lale Karabıyık
author_sort Selin Erel
collection DOAJ
description Objective: The negative effects of delirium in intensive care unit (ICU) patients necessitate the identification and management of risk factors. This study aimed to determine the incidence of delirium and its associated modifiable and non-modifiable factors in the ICU setting to provide valuable insights for better patient care and outcomes. Methods: Patients admitted to the ICU underwent delirium screening twice daily. Comprehensive records of modifiable and non-modifiable risk factors were maintained throughout the ICU stay. Results: The incidence of delirium was 32.5%. Age [odds ratio (OR) 1.04, confidence interval (CI) 1.02-1.06, P < 0.001)]. Illiteracy (OR 4, CI 1.19-13.35, P=0.02), hearing impairment (OR 3.37, CI 1.71-7.01, P=0.001), visual impairment (OR 3.90, CI 2.13-7.15, P < 0.001), hypertension (OR 2.56, CI 1.42-4.62, P=0.002), Sequential Organ Failure Assessment score (OR 1.21, CI 1.08-1.36, P=0.001), Acute Physiology and Chronic Health Evaluation II score (OR 1.20, CI 1.12-1.28, P < 0.001), presence of a nasogastric catheter/drain (OR 2.15, CI 1.18-3. 90, P=0.01), tracheal aspiration (OR 3.63, CI 1.91-6.90, P < 0.001), enteral nutrition (OR 2.54, CI 1.12-5.76, P=0.02), constipation (OR 1.65, Cl 1.11-2.45, P=0.02), oliguria (OR 1.56, Cl 1.06-2.28, P=0.02), midazolam infusion (OR 3. 4, Cl 1.16-10.05, P=0.02), propofol infusion (OR 2.91 Cl 1.03-8.19, P=0.04), albumin use (OR 2.39, Cl 1.11-5.14 P=0.02) and steroid use (OR 2.17, Cl 1.06-4.40, P=0.03) were found to be independent risk factors for delirium. Conclusion: This study highlights several risk factors contributing to delirium, such as age, sensory impairment, educational level, procedural interventions, and medications.Oral nutrition and mobilization are effective strategies for reducing delirium incidence in the ICU.
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spelling doaj-art-a78dbed2099a4cf5bfb01034d73a37612024-12-17T11:08:25ZengGalenos Publishing HouseTurkish Journal of Anaesthesiology and Reanimation2667-63702024-12-0152621322210.4274/TJAR.2024.241526Evaluation of Delirium Risk Factors in Intensive Care PatientsSelin Erel0https://orcid.org/0000-0002-6040-9815Eda Macit Aydın1https://orcid.org/0000-0002-4607-4932Bijen Nazlıel2https://orcid.org/0000-0002-6148-3814Lale Karabıyık3https://orcid.org/0000-0002-6009-8324Gazi University Faculty of Medicine, Department of Anaesthesiology and Reanimation, Ankara, TurkeyGazi University Faculty of Medicine, Department of Anaesthesiology and Reanimation, Division of Intensive Care, Ankara, TurkeyGazi University Faculty of Medicine, Department of Neurology, Ankara, TurkeyGazi University Faculty of Medicine, Department of Anaesthesiology and Reanimation, Ankara, TurkeyObjective: The negative effects of delirium in intensive care unit (ICU) patients necessitate the identification and management of risk factors. This study aimed to determine the incidence of delirium and its associated modifiable and non-modifiable factors in the ICU setting to provide valuable insights for better patient care and outcomes. Methods: Patients admitted to the ICU underwent delirium screening twice daily. Comprehensive records of modifiable and non-modifiable risk factors were maintained throughout the ICU stay. Results: The incidence of delirium was 32.5%. Age [odds ratio (OR) 1.04, confidence interval (CI) 1.02-1.06, P < 0.001)]. Illiteracy (OR 4, CI 1.19-13.35, P=0.02), hearing impairment (OR 3.37, CI 1.71-7.01, P=0.001), visual impairment (OR 3.90, CI 2.13-7.15, P < 0.001), hypertension (OR 2.56, CI 1.42-4.62, P=0.002), Sequential Organ Failure Assessment score (OR 1.21, CI 1.08-1.36, P=0.001), Acute Physiology and Chronic Health Evaluation II score (OR 1.20, CI 1.12-1.28, P < 0.001), presence of a nasogastric catheter/drain (OR 2.15, CI 1.18-3. 90, P=0.01), tracheal aspiration (OR 3.63, CI 1.91-6.90, P < 0.001), enteral nutrition (OR 2.54, CI 1.12-5.76, P=0.02), constipation (OR 1.65, Cl 1.11-2.45, P=0.02), oliguria (OR 1.56, Cl 1.06-2.28, P=0.02), midazolam infusion (OR 3. 4, Cl 1.16-10.05, P=0.02), propofol infusion (OR 2.91 Cl 1.03-8.19, P=0.04), albumin use (OR 2.39, Cl 1.11-5.14 P=0.02) and steroid use (OR 2.17, Cl 1.06-4.40, P=0.03) were found to be independent risk factors for delirium. Conclusion: This study highlights several risk factors contributing to delirium, such as age, sensory impairment, educational level, procedural interventions, and medications.Oral nutrition and mobilization are effective strategies for reducing delirium incidence in the ICU.https://turkjanaesthesiolreanim.org/articles/evaluation-of-delirium-risk-factors-in-intensive-care-patients/doi/TJAR.2024.241526cognition disorderscritical caredeliriumincidencerisk
spellingShingle Selin Erel
Eda Macit Aydın
Bijen Nazlıel
Lale Karabıyık
Evaluation of Delirium Risk Factors in Intensive Care Patients
Turkish Journal of Anaesthesiology and Reanimation
cognition disorders
critical care
delirium
incidence
risk
title Evaluation of Delirium Risk Factors in Intensive Care Patients
title_full Evaluation of Delirium Risk Factors in Intensive Care Patients
title_fullStr Evaluation of Delirium Risk Factors in Intensive Care Patients
title_full_unstemmed Evaluation of Delirium Risk Factors in Intensive Care Patients
title_short Evaluation of Delirium Risk Factors in Intensive Care Patients
title_sort evaluation of delirium risk factors in intensive care patients
topic cognition disorders
critical care
delirium
incidence
risk
url https://turkjanaesthesiolreanim.org/articles/evaluation-of-delirium-risk-factors-in-intensive-care-patients/doi/TJAR.2024.241526
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AT bijennazlıel evaluationofdeliriumriskfactorsinintensivecarepatients
AT lalekarabıyık evaluationofdeliriumriskfactorsinintensivecarepatients