Left Ventricular Assist Devices – Past, Present, and Future: A Narrative Review
Advanced heart failure (AHF) is a major problem with an aging population and profound unmet needs. While heart transplant offers the most definitive solution, it is largely unavailable for most and mandates a long waiting period. Left ventricular assist devices (LVADs) help in expanding the treatmen...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-12-01
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| Series: | Journal of the Practice of Cardiovascular Sciences |
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| Online Access: | https://journals.lww.com/10.4103/jpcs.jpcs_62_24 |
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| author | Devesh Kumar Sandeep Seth Rajiv Narang |
| author_facet | Devesh Kumar Sandeep Seth Rajiv Narang |
| author_sort | Devesh Kumar |
| collection | DOAJ |
| description | Advanced heart failure (AHF) is a major problem with an aging population and profound unmet needs. While heart transplant offers the most definitive solution, it is largely unavailable for most and mandates a long waiting period. Left ventricular assist devices (LVADs) help in expanding the treatment armamentarium to those for whom transplant is either a contraindication or unavailable (destination therapy) and those who need stabilization before transplant (bridge to transplant). LVADs are truly a renaissance in the management of AHF as they make treatment available to a much larger population and improve not only symptoms and quality of life but also survival as compared to patients on medical therapy only. Consequently, they have now been adopted in many European centres as destination therapy with a median survival of 7 years in patients with a LVAD implantation. LVADS are plagued with multiple complications, and while they do offer an opportunity of improved survival, the patients often are plagued with morbid complications. Newer advances in technology have paved the way for smaller and better engineered devices with lesser complications like bleeding and pump thrombosis. We review briefly the burden of advanced Heart Failure, evolution of LVADs, current status and the future of these devices. |
| format | Article |
| id | doaj-art-a788041be8ff41119a71078b28926fd5 |
| institution | Kabale University |
| issn | 2395-5414 2454-2830 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of the Practice of Cardiovascular Sciences |
| spelling | doaj-art-a788041be8ff41119a71078b28926fd52025-01-14T05:54:35ZengWolters Kluwer Medknow PublicationsJournal of the Practice of Cardiovascular Sciences2395-54142454-28302024-12-0110313113610.4103/jpcs.jpcs_62_24Left Ventricular Assist Devices – Past, Present, and Future: A Narrative ReviewDevesh KumarSandeep SethRajiv NarangAdvanced heart failure (AHF) is a major problem with an aging population and profound unmet needs. While heart transplant offers the most definitive solution, it is largely unavailable for most and mandates a long waiting period. Left ventricular assist devices (LVADs) help in expanding the treatment armamentarium to those for whom transplant is either a contraindication or unavailable (destination therapy) and those who need stabilization before transplant (bridge to transplant). LVADs are truly a renaissance in the management of AHF as they make treatment available to a much larger population and improve not only symptoms and quality of life but also survival as compared to patients on medical therapy only. Consequently, they have now been adopted in many European centres as destination therapy with a median survival of 7 years in patients with a LVAD implantation. LVADS are plagued with multiple complications, and while they do offer an opportunity of improved survival, the patients often are plagued with morbid complications. Newer advances in technology have paved the way for smaller and better engineered devices with lesser complications like bleeding and pump thrombosis. We review briefly the burden of advanced Heart Failure, evolution of LVADs, current status and the future of these devices.https://journals.lww.com/10.4103/jpcs.jpcs_62_24advanced heart failurecardiac transplantcomplications of left ventricular assist devicesleft ventricular assist devices |
| spellingShingle | Devesh Kumar Sandeep Seth Rajiv Narang Left Ventricular Assist Devices – Past, Present, and Future: A Narrative Review Journal of the Practice of Cardiovascular Sciences advanced heart failure cardiac transplant complications of left ventricular assist devices left ventricular assist devices |
| title | Left Ventricular Assist Devices – Past, Present, and Future: A Narrative Review |
| title_full | Left Ventricular Assist Devices – Past, Present, and Future: A Narrative Review |
| title_fullStr | Left Ventricular Assist Devices – Past, Present, and Future: A Narrative Review |
| title_full_unstemmed | Left Ventricular Assist Devices – Past, Present, and Future: A Narrative Review |
| title_short | Left Ventricular Assist Devices – Past, Present, and Future: A Narrative Review |
| title_sort | left ventricular assist devices past present and future a narrative review |
| topic | advanced heart failure cardiac transplant complications of left ventricular assist devices left ventricular assist devices |
| url | https://journals.lww.com/10.4103/jpcs.jpcs_62_24 |
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