Dabie bandavirus and Mycoplasma pneumoniae co-infection: a case report

Abstract Background Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease caused by Dabie bandavirus (DBV). We report a case of DBV and Mycoplasma pneumoniae (MP) co-infection. Case presentation Here we reported a 57-year-old healthy male who was admitted with the pres...

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Bibliographic Details
Main Authors: Yasi Tu, Miao Deng, Xueying Zhang, Tianxin Xiang, Daxian Wu
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Infectious Diseases
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Online Access:https://doi.org/10.1186/s12879-024-10392-2
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Summary:Abstract Background Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease caused by Dabie bandavirus (DBV). We report a case of DBV and Mycoplasma pneumoniae (MP) co-infection. Case presentation Here we reported a 57-year-old healthy male who was admitted with the presentations of fever, cough, hemoptysis, and hypotension. Laboratory investigations revealed thrombocytopenia, leukopenia, and organ dysfunction of liver and kidney. Seroconversion from Mycoplasma IgM antibody to IgG was recorded, and SFTS was confirmed through metagenomic next-generation sequencing. In addition, hemophagocytic lymphohistiocytosis was diagnosed in the context of DBV and MP coinfection. The patient exhibited a rapid recovery following treatment with omadacycline and essential symptomatic and supportive treatment. Conclusions We firstly reported a case with DBV and MP coinfection, which reminded us that the symptoms of DBV infection were bewildering and easy to miss diagnosis when it was co-infection with other etiologies.
ISSN:1471-2334