Glucocorticoid-Induced Tumour Necrosis Factor Receptor-Related Protein: A Key Marker of Functional Regulatory T Cells
Glucocorticoid-induced tumour necrosis factor receptor-related protein (GITR, TNFRSF18, and CD357) is expressed at high levels in activated T cells and regulatory T cells (Tregs). In this review, we present data from mouse and human studies suggesting that GITR is a crucial player in the differentia...
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Main Authors: | Simona Ronchetti, Erika Ricci, Maria Grazia Petrillo, Luigi Cari, Graziella Migliorati, Giuseppe Nocentini, Carlo Riccardi |
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Format: | Article |
Language: | English |
Published: |
Wiley
2015-01-01
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Series: | Journal of Immunology Research |
Online Access: | http://dx.doi.org/10.1155/2015/171520 |
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