Structural characterization and prebiotic potential of polysaccharides from Polygonatum sibiricum
Polygonatum sibiricum has been widely used due to its excellent biological activities. We prepared a novel polysaccharide from P. sibiricum (PSP) in this study. According a monosaccharide composition analysis, PSP was mainly composed of fructose and glucose with a molar percentage of 93.81:5.12. The...
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Tsinghua University Press
2024-07-01
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| Series: | Food Science and Human Wellness |
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| Online Access: | https://www.sciopen.com/article/10.26599/FSHW.2022.9250184 |
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| author | Zihan Qi Tiexiang Gao Jingjing Li Shuhan Zhou Zhigang Zhang Mingzhu Yin Haiming Hu Hongtao Liu |
| author_facet | Zihan Qi Tiexiang Gao Jingjing Li Shuhan Zhou Zhigang Zhang Mingzhu Yin Haiming Hu Hongtao Liu |
| author_sort | Zihan Qi |
| collection | DOAJ |
| description | Polygonatum sibiricum has been widely used due to its excellent biological activities. We prepared a novel polysaccharide from P. sibiricum (PSP) in this study. According a monosaccharide composition analysis, PSP was mainly composed of fructose and glucose with a molar percentage of 93.81:5.12. The main linkage types were identified as α-D-Glcp-1→ and →2-β-D-Fruf-1→. The molecular weight of PSP showed no significant change after simulated salivary and gastrointestinal digestion. However, PSP could be broken down by intestinal bacteria. Our findings revealed that PSP administration increased the abundance of probiotics such as Bifi dobacterium. Furthermore, the results showed that gut microbes could utilize PSP to produce short-chain fatty acids including acetic acid, propionic acid, and butyric acid. Also, the PSP fermentation broth displayed an excellent scavenging effect on free radicals, including 2, 2-diphenyl-1-picrylhydrazyl radical, superoxide radical, and hydroxyl radical. In summary, this study will help to promote the application of PSP as prebiotics in functional food and the medical industry. |
| format | Article |
| id | doaj-art-a6d2f7503135420084fa5bcf219cf768 |
| institution | Kabale University |
| issn | 2097-0765 2213-4530 |
| language | English |
| publishDate | 2024-07-01 |
| publisher | Tsinghua University Press |
| record_format | Article |
| series | Food Science and Human Wellness |
| spelling | doaj-art-a6d2f7503135420084fa5bcf219cf7682025-01-10T06:56:48ZengTsinghua University PressFood Science and Human Wellness2097-07652213-45302024-07-011342208222010.26599/FSHW.2022.9250184Structural characterization and prebiotic potential of polysaccharides from Polygonatum sibiricumZihan Qi0Tiexiang Gao1Jingjing Li2Shuhan Zhou3Zhigang Zhang4Mingzhu Yin5Haiming Hu6Hongtao Liu7College of Basic Medical Sciences, Hubei University of Chinese Medicine, Wuhan 430065, ChinaCollege of Pharmacy, Hubei University of Chinese Medicine, Wuhan 430065, ChinaCollege of Basic Medical Sciences, Hubei University of Chinese Medicine, Wuhan 430065, ChinaCollege of Basic Medical Sciences, Hubei University of Chinese Medicine, Wuhan 430065, ChinaCollege of Basic Medical Sciences, Hubei University of Chinese Medicine, Wuhan 430065, ChinaCollege of Basic Medical Sciences, Hubei University of Chinese Medicine, Wuhan 430065, ChinaCollege of Basic Medical Sciences, Hubei University of Chinese Medicine, Wuhan 430065, ChinaCollege of Basic Medical Sciences, Hubei University of Chinese Medicine, Wuhan 430065, ChinaPolygonatum sibiricum has been widely used due to its excellent biological activities. We prepared a novel polysaccharide from P. sibiricum (PSP) in this study. According a monosaccharide composition analysis, PSP was mainly composed of fructose and glucose with a molar percentage of 93.81:5.12. The main linkage types were identified as α-D-Glcp-1→ and →2-β-D-Fruf-1→. The molecular weight of PSP showed no significant change after simulated salivary and gastrointestinal digestion. However, PSP could be broken down by intestinal bacteria. Our findings revealed that PSP administration increased the abundance of probiotics such as Bifi dobacterium. Furthermore, the results showed that gut microbes could utilize PSP to produce short-chain fatty acids including acetic acid, propionic acid, and butyric acid. Also, the PSP fermentation broth displayed an excellent scavenging effect on free radicals, including 2, 2-diphenyl-1-picrylhydrazyl radical, superoxide radical, and hydroxyl radical. In summary, this study will help to promote the application of PSP as prebiotics in functional food and the medical industry.https://www.sciopen.com/article/10.26599/FSHW.2022.9250184dietary polysaccharidesprebioticgut microbiotashort-chain fatty acids |
| spellingShingle | Zihan Qi Tiexiang Gao Jingjing Li Shuhan Zhou Zhigang Zhang Mingzhu Yin Haiming Hu Hongtao Liu Structural characterization and prebiotic potential of polysaccharides from Polygonatum sibiricum Food Science and Human Wellness dietary polysaccharides prebiotic gut microbiota short-chain fatty acids |
| title | Structural characterization and prebiotic potential of polysaccharides from Polygonatum sibiricum |
| title_full | Structural characterization and prebiotic potential of polysaccharides from Polygonatum sibiricum |
| title_fullStr | Structural characterization and prebiotic potential of polysaccharides from Polygonatum sibiricum |
| title_full_unstemmed | Structural characterization and prebiotic potential of polysaccharides from Polygonatum sibiricum |
| title_short | Structural characterization and prebiotic potential of polysaccharides from Polygonatum sibiricum |
| title_sort | structural characterization and prebiotic potential of polysaccharides from polygonatum sibiricum |
| topic | dietary polysaccharides prebiotic gut microbiota short-chain fatty acids |
| url | https://www.sciopen.com/article/10.26599/FSHW.2022.9250184 |
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