Panniculitis in Anti-MDA-5 Positive Juvenile Dermatomyositis: A Case Report

Panniculitis is a rare clinical finding in dermatomyositis. There are few reported cases in the medical literature. In this report, we describe a 17-year-old male patient with anti-MDA5 positive hypomyopathic dermatomyositis who, eight months after diagnosis, presented with indurated nodules on the...

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Main Authors: Semra Ayduran, Gulsah Kilbas, Saadet Nilay Tigrak, Selcuk Yuksel, Erdem Comut, Serkan Turkucar
Format: Article
Language:English
Published: Nepal Medical Association 2024-12-01
Series:Journal of Nepal Medical Association
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Online Access:https://www.jnma.com.np/jnma/index.php/jnma/article/view/8874
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author Semra Ayduran
Gulsah Kilbas
Saadet Nilay Tigrak
Selcuk Yuksel
Erdem Comut
Serkan Turkucar
author_facet Semra Ayduran
Gulsah Kilbas
Saadet Nilay Tigrak
Selcuk Yuksel
Erdem Comut
Serkan Turkucar
author_sort Semra Ayduran
collection DOAJ
description Panniculitis is a rare clinical finding in dermatomyositis. There are few reported cases in the medical literature. In this report, we describe a 17-year-old male patient with anti-MDA5 positive hypomyopathic dermatomyositis who, eight months after diagnosis, presented with indurated nodules on the right forearm and right thigh despite methotrexate and monthly intravenous immunoglobulin treatment. A skin biopsy revealed lobular panniculitis with lymphocytic infiltrate. His lesions were successfully controlled with hydroxychloroquine and azathioprine. This article presents a case regarding the rarity of panniculitis in juvenile dermatomyositis and its treatment strategy.
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institution Kabale University
issn 0028-2715
1815-672X
language English
publishDate 2024-12-01
publisher Nepal Medical Association
record_format Article
series Journal of Nepal Medical Association
spelling doaj-art-a6a795f4b08d421aa85494dfa9f282422025-01-03T09:12:30ZengNepal Medical AssociationJournal of Nepal Medical Association0028-27151815-672X2024-12-016328110.31729/jnma.8874Panniculitis in Anti-MDA-5 Positive Juvenile Dermatomyositis: A Case ReportSemra Ayduran0Gulsah Kilbas1Saadet Nilay Tigrak2Selcuk Yuksel3Erdem Comut4Serkan Turkucar5Department of Pediatric Rheumatology, Pamukkale University, Denizli, TurkiyeDepartment of Pediatric Rheumatology, Pamukkale University, Denizli, TurkiyeDepartment of Pediatric Rheumatology, Pamukkale University, Denizli, TurkiyeDepartment of Pediatric Rheumatology, Canakkale Onsekiz Mart University, Canakkale, TurkiyeDepartment of Pathology, Pamukkale University, Pathology, Denizli, TurkiyeDepartment of Pediatric Rheumatology, Pamukkale University, Denizli, Turkiye Panniculitis is a rare clinical finding in dermatomyositis. There are few reported cases in the medical literature. In this report, we describe a 17-year-old male patient with anti-MDA5 positive hypomyopathic dermatomyositis who, eight months after diagnosis, presented with indurated nodules on the right forearm and right thigh despite methotrexate and monthly intravenous immunoglobulin treatment. A skin biopsy revealed lobular panniculitis with lymphocytic infiltrate. His lesions were successfully controlled with hydroxychloroquine and azathioprine. This article presents a case regarding the rarity of panniculitis in juvenile dermatomyositis and its treatment strategy. https://www.jnma.com.np/jnma/index.php/jnma/article/view/8874anti MDA-5dermatomyositispanniculitis
spellingShingle Semra Ayduran
Gulsah Kilbas
Saadet Nilay Tigrak
Selcuk Yuksel
Erdem Comut
Serkan Turkucar
Panniculitis in Anti-MDA-5 Positive Juvenile Dermatomyositis: A Case Report
Journal of Nepal Medical Association
anti MDA-5
dermatomyositis
panniculitis
title Panniculitis in Anti-MDA-5 Positive Juvenile Dermatomyositis: A Case Report
title_full Panniculitis in Anti-MDA-5 Positive Juvenile Dermatomyositis: A Case Report
title_fullStr Panniculitis in Anti-MDA-5 Positive Juvenile Dermatomyositis: A Case Report
title_full_unstemmed Panniculitis in Anti-MDA-5 Positive Juvenile Dermatomyositis: A Case Report
title_short Panniculitis in Anti-MDA-5 Positive Juvenile Dermatomyositis: A Case Report
title_sort panniculitis in anti mda 5 positive juvenile dermatomyositis a case report
topic anti MDA-5
dermatomyositis
panniculitis
url https://www.jnma.com.np/jnma/index.php/jnma/article/view/8874
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AT selcukyuksel panniculitisinantimda5positivejuveniledermatomyositisacasereport
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