Interplay of aurora kinase a functional residues and Epstein-barr Nuclear Antigen 1 in Epstein-barr virus associated Gastric cancer using AGS cells

Interplay of aurora kinase a functional residues and Epstein-barr Nuclear Antigen 1 in Epstein-barr virus associated Gastric cancer using AGS cells

Abstract Epstein-Barr virus (EBV), an oncogenic gamma-herpesvirus, belongs to group 1 carcinogen and is implicated in various cancers, including gastric cancer. Aurora Kinase A is a major mitotic protein kinase that regulates mitotic progression; overexpression and hyperactivation of AURKA commonly...

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Bibliographic Details
Main Authors: Nidhi Varshney, Siddharth Singh, Meenakshi Kandpal, Vaishali Saini, Erle S. Roberston, Hem Chandra Jha
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Cancer
Subjects:
Aurora Kinase A
Gastric cancer
Epstein-Barr Virus
Epstein-Barr Nuclear Antigen 1
Microtubule polymerisation
Stability assay
Online Access:https://doi.org/10.1186/s12885-024-13260-z
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