Antimicrobial activity and mechanistic insights of AMP-17 against drug-resistant Pseudomonas aeruginosa and its efficacy in wound infection management

Antimicrobial activity and mechanistic insights of AMP-17 against drug-resistant Pseudomonas aeruginosa and its efficacy in wound infection management

IntroductionChronic wound infections caused by drug-resistant bacteria have emerged as a global health challenge, affecting millions of patients annually and imposing a substantial economic and societal burden. However, current therapeutic approaches exhibit limited efficacy in treating drug-resista...

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Main Authors: Ruyu Tao, Chunren Tian, Ting Su, Ruxia Cai, Dongxu Song, Na Zhao, Yuansan Lei, Zhenlong Jiao, Guo Guo
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
AMP-17
Pseudomonas aeruginosa
antimicrobial peptide
wound infection
mechanism of action
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2025.1634825/full
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