First-trimester triglyceride-glucose index and birth weight: a retrospective cohort mediation analysis of preterm birth and gestational complications

First-trimester triglyceride-glucose index and birth weight: a retrospective cohort mediation analysis of preterm birth and gestational complications

Abstract Background Insulin resistance during pregnancy, while physiologically adaptive to enhance fetal nutrient supply, becomes pathological when excessive, contributing to low birth weight (LBW). The triglyceride-glucose (TyG) index, a biomarker of insulin resistance, predicts gestational complic...

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Bibliographic Details
Main Authors: Jinhui Cui, Hui Jiang, Fei Huang, Mengjun Xie, Ziyi Cui, Xinyuan Chen, Liping OUYang, Ping Li, Yanling Wang
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Pregnancy and Childbirth
Subjects:
TyG index
Preterm birth
Low birth weight
Gestational complications
Insulin resistance
Causal mediation analysis
Online Access:https://doi.org/10.1186/s12884-025-07885-6
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