Generalized bacterial genome editing using mobile group II introns and Cre‐lox

Generalized bacterial genome editing using mobile group II introns and Cre‐lox

Abstract Efficient bacterial genetic engineering approaches with broad‐host applicability are rare. We combine two systems, mobile group II introns (‘targetrons’) and Cre/lox, which function efficiently in many different organisms, into a versatile platform we call GETR (Genome Editing via Targetron...

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Bibliographic Details
Main Authors: Peter J Enyeart, Steven M Chirieleison, Mai N Dao, Jiri Perutka, Erik M Quandt, Jun Yao, Jacob T Whitt, Adrian T Keatinge‐Clay, Alan M Lambowitz, Andrew D Ellington
Format: Article
Language:English
Published: Springer Nature 2013-09-01
Series:Molecular Systems Biology
Subjects:
bacterial genome engineering
Cre‐lox
mobile group II introns
Staphylococcus aureus
Shewanella oneidensis
Online Access:https://doi.org/10.1038/msb.2013.41
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https://doi.org/10.1038/msb.2013.41

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