Tenecteplase Versus Alteplase in Acute Ischemic Stroke in Chinese Patients: Protocol for the ORIGINAL Study

Tenecteplase Versus Alteplase in Acute Ischemic Stroke in Chinese Patients: Protocol for the ORIGINAL Study

Background Tenecteplase, a bioengineered variant of alteplase, is a new alternative thrombolytic agent. The ORIGINAL study aims to evaluate the efficacy and safety of tenecteplase versus standard care in Chinese patients with acute ischemic stroke within 4.5 hours of symptom onset. Methods This is a...

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Bibliographic Details
Main Authors: Xia Meng, Shuya Li, Hongguo Dai, Guozhi Lu, Weiwei Wang, Fengyuan Che, Yu Geng, Minghui Sun, Xiyan Li, Yongjun Wang
Format: Article
Language:English
Published: Wiley 2024-07-01
Series:Stroke: Vascular and Interventional Neurology
Subjects:
alteplase
Chinese
functional outcome
ischemic stroke
symptomatic intracerebral hemorrhage
tenecteplase
Online Access:https://www.ahajournals.org/doi/10.1161/SVIN.124.001363
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https://www.ahajournals.org/doi/10.1161/SVIN.124.001363

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