Monosaccharide coatings on nanoparticles affect protein corona formation but not the interaction with their binding receptor

Monosaccharide coatings on nanoparticles affect protein corona formation but not the interaction with their binding receptor

Surface coatings with polyethylene glycol (PEG) polymers have often been employed to improve nanoparticles (NPs) biocompatibility and extend circulation time by reducing protein adsorption. PEGylated NPs benefit from steric hindrance and repulsion effects, which are influenced by PEG molecular weigh...

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Bibliographic Details
Main Authors: Eva Clemente, Ruth Mateu, Avelino Ferreira, Tanja Ludtke, Hender Lopez, Sergio E. Moya, Luigi Lay, Mahmoud G. Soliman, Marco P. Monopoli
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Nanotechnology
Subjects:
gold nanoparticles
glycans
protein corona
colloidal stability
active targeting
PEGylation processes
Online Access:https://www.frontiersin.org/articles/10.3389/fnano.2024.1505757/full
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