The effects of systemic and sustained hypoxia on orthodontic tooth movement in rats

The effects of systemic and sustained hypoxia on orthodontic tooth movement in rats

Abstract During orthodontic tooth movement (OTM), local hypoxia on the compression side stimulates cellular remodelling of periodontal tissues. We investigated the effects of systemic, sustained hypoxia on OTM in vivo. OTM was performed on the right maxillary first molar (M1) of 8-week-old male Spra...

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Bibliographic Details
Main Authors: Kwanrat Ploysongsang, Yukiho Kobayashi, Yeming Lu, Yuki Niki, Janeta Chavanavesh, Keiji Moriyama
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Orthodontic tooth movement
Hypoxia
Periodontal ligament
Osteoblast
Osteoclast
Online Access:https://doi.org/10.1038/s41598-025-07949-9
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