Acetyltransferase NAT10 promotes an immunosuppressive microenvironment by modulating CD8+ T cell activity in prostate cancer

Acetyltransferase NAT10 promotes an immunosuppressive microenvironment by modulating CD8+ T cell activity in prostate cancer

Abstract N-acetyltransferase 10 (NAT10), an enzyme responsible for ac4C acetylation, is implicated in cancer progression, though its specific biological function in prostate cancer remains insufficiently understood. This study clarifies NAT10’s role in prostate cancer and its effects on the tumor im...

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Bibliographic Details
Main Authors: Ji Liu, Zhuoran Gu, Libin Zou, Zhijin Zhang, Liliang Shen, Ruiliang Wang, Shaobo Xue, Jiang Geng, Shiyu Mao, Wentao Zhang, Xudong Yao
Format: Article
Language:English
Published: Springer 2024-12-01
Series:Molecular Biomedicine
Subjects:
Prostate cancer
Ac4C acetylation
Immune microenvironment
Immunotherapy
Online Access:https://doi.org/10.1186/s43556-024-00228-5
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