Biliary atresia susceptibility gene EFEMP1 regulates extrahepatic bile duct elastic fiber formation and mechanics
Background & Aims: EGF-containing fibulin extracellular matrix protein 1 (EFEMP1, also called fibulin-3) is an extracellular matrix protein linked in a genome-wide association study to biliary atresia, a fibrotic disease of the neonatal extrahepatic bile duct. Fibulin-3 is deposited in most...
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Main Authors: | Kapish Gupta, Jessica Llewellyn, Emilia Roberts, Chengyang Liu, Ali Naji, Richard K. Assoian, Rebecca G. Wells |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2025-01-01
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Series: | JHEP Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2589555924002192 |
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