Pharmacometabolomics Approach to Explore Pharmacokinetic Variation and Clinical Characteristics of a Single Dose of Desvenlafaxine in Healthy Volunteers

Pharmacometabolomics Approach to Explore Pharmacokinetic Variation and Clinical Characteristics of a Single Dose of Desvenlafaxine in Healthy Volunteers

This study investigated the effects of a single dose of desvenlafaxine via oral administration on the pharmacokinetic parameters and clinical and laboratory characteristics in healthy volunteers using a pharmacometabolomics approach. In order to optimize desvenlafaxine’s therapeutic use and minimize...

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Bibliographic Details
Main Authors: Anne Michelli Reis Silveira, Salvador Sánchez-Vinces, Alex Ap. Rosini Silva, Karen Sánchez-Luquez, Pedro Henrique Dias Garcia, Caroline de Moura Garcia, Rhubia Bethania Socorro Lemos de Brito, Ana Lais Vieira, Lucas Miguel de Carvalho, Marcia Ap. Antonio, Patrícia de Oliveira Carvalho
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Pharmaceutics
Subjects:
desvenlafaxine
metabolomics profile
metabolic pathways
pharmacokinetics
Online Access:https://www.mdpi.com/1999-4923/16/11/1385
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