SAFETY STUDY OF ROMIPLOSTIM BIOSIMILAR

SAFETY STUDY OF ROMIPLOSTIM BIOSIMILAR

Idiopathic thrombocytopenic purpura is a chronic autoimmune hematological disease caused by an increased destruction of platelets and associated thrombocytopenia, for the treatment of which the imported drug romiplostim is used. Сreation of the drug biosimilar provides a reduction in the cost of the...

Full description

Saved in:

Bibliographic Details
Main Authors:	A. N. Afanasyeva, V. B. Saparova, D. D. Karal-Ogly, E. I. Mukhametzyanova, D. V. Kurkin, A. V. Kalatanova, I. E. Makarenko, A. L. Khokhlov, I. A. Lugovik
Format:	Article
Language:	Russian
Published:	Volgograd State Medical University, Pyatigorsk Medical and Pharmaceutical Institute 2022-10-01
Series:	Фармация и фармакология (Пятигорск)
Subjects:	romiplostim biosimilar gp40141 nplate® complement-dependent cytotoxicity drug safety studies in vivo in vitro idiopathic thrombocytopenic purpura toxicological profile thrombopoietin receptor tpo-r
Online Access:	https://www.pharmpharm.ru/jour/article/view/1165
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Thrombopoietin mutation in congenital amegakaryocytic thrombocytopenia treatable with romiplostim
by: Alessandro Pecci, et al.
Published: (2017-11-01)

Thrombopoietin Receptor Agonists: Clinical Use and Evaluation of Treatment Efficacy
by: A. G. Solodovnikov, et al.
Published: (2020-12-01)

Urogenital haemorrhage secondary to Babesia gibsoni induced immune thrombocytopenia and its management with combination of romiplostim and prednisolone in a dog
by: Nadima Khan, et al.
Published: (2025-06-01)

Should thrombopoietin receptor agonists be used for chemotherapy-induced thrombocytopenia?
by: Hanny Al-Samkari
Published: (2025-07-01)

Real-world experience of hetrombopag in immune thrombocytopenia treatment: a retrospective cohort study
by: Dan Wang, et al.
Published: (2025-07-01)

CAUSES OF DEVELOPMENT OF ACUTE AND CHRONIC THROMBOCYTOPENIA IN CHILDREN OF IRKUTSK REGION
by: N. N. Martynovich, et al.
Published: (2018-09-01)

Thrombotic Thrombocytopenic Purpura as a Rare Etiopathogenetic Cause of Cerebral Infarction and Extracerebral Thrombosis
by: А. R. Аvidzba, et al.
Published: (2021-08-01)

Immune thrombocytopenia: literature review
by: S. G. Zakharov
Published: (2024-09-01)

The art of holistic care: What should the GP know?
by: D. van Velden
Published: (1998-02-01)

Correction of Thrombocytopenia with Thrombopoietin Receptor Agonists in Patients with Liver Cirrhosis Before Elective Surgery or Invasive Procedures
by: T. A. Deeva, et al.
Published: (2025-02-01)

Tyrosine kinase inhibitors therapy related neutropenia and thrombocythopenia correction in CML patients
by: V. A. Shuvaev, et al.
Published: (2014-07-01)

Idiopathic Thrombocytopenic Purpura as Initial Manifestation of Systemic Lupus Erythematosus: A Case Report
by: Fatih Bağcıer, et al.
Published: (2016-08-01)

Preliminary investigation of the epigenetic regulation of KMT2D via H3K4me1/H3K27ac in oral squamous cell carcinoma
by: Mujie Yuan, et al.
Published: (2025-06-01)

Intrahospital switch of the P2Y12 inhibitors in patients with ST segment elevation myocardial infarction in ‘real-life’ clinical practice: the effect on the functional activity of thrombocytes and thrombocytopoiesis, prognostic value
by: L. I. Malinova, et al.
Published: (2019-09-01)

Recombinant human thrombopoietin improves hematopoietic stem cell differentiation and T-cell immune homeostasis in patients with severe aplastic anemia by upregulating c-MPL
by: Ling Deng, et al.
Published: (2025-08-01)

Early caplacizumab and obinutuzumab enable successful treatment of relapsing thrombotic thrombocytopenic purpura without therapeutic plasma exchange: a case report
by: Judith Schimpf, et al.
Published: (2025-04-01)

Clinical observation of severe novel coronavirus infection COVID-19 that complicated the postpartum period in puerpera after caesarean section
by: L. I. Maltseva, et al.
Published: (2021-07-01)

Correlations between expression levels of genes encoding multifunctional YB-1 protein, inflammatory cytokines and multidrug resistance P-gp protein in surgical material from patients with lung tuberculosis
by: M. V. Erokhina, et al.
Published: (2025-03-01)

Dose-optimised recombinant human thrombopoietin versus eltrombopag in patients with immune thrombocytopenia: a multicenter, randomised controlled trial (The TE-ITP Study)Research in context
by: Yunfei Chen, et al.
Published: (2025-09-01)

Triple antiviral therapy in patient with liver cirrhosis: complications and options of pharmacological treatment
by: M. V. Mayevskaya, et al.
Published: (2014-08-01)

Acute myocardial infarction induced by avatrombopag: a case report
by: Gou Junqi, et al.
Published: (2025-08-01)

Intravenous immunoglobulin: prospects in patients with autoimmune rheumatic diseases
by: Elena Aleksandrovna Aseeva, et al.
Published: (2014-03-01)

A review of recent Cryptosporidium hominis and Cryptosporidium parvum gp60 subtypes
by: Deborah B. Oladele, et al.
Published: (2025-01-01)

Circulating Progranulin: A Promising Novel Diagnostic and Prognostic Biomarker in Canine Oncology
by: Keon Kim, et al.
Published: (2025-05-01)

The contribution of Specialist Family Physicians to South Africa’s private sector: A position statement
by: Gail L. Ashford, et al.
Published: (2024-10-01)

Context dependent role of miR-486 promoting neuroregeneration of primary sensory neurons downstream of interleukin-6 signal transducer
by: Theodora Kalpachidou, et al.
Published: (2025-09-01)

A case with a novel GATA1 variant mimicking immune thrombocytopenia attacks
by: Elif Habibe Aktekin, et al.
Published: (2025-12-01)

POSSIBILITIES OF CLINICAL LABORATORY EVALUATION OF ANTIPLATELET THERAPY EFFECTIVENESS IN PATIENTS WITH ISCHEMIC HEART DISEASE
by: O. V. Sirotkina, et al.
Published: (2015-09-01)

Neurodiversity: bridging the gap in UK's GP training for a more inclusive future
by: Waseem Jerjes, et al.
Published: (2025-08-01)

Bioanalogues in the treatment of rheumatoid arthritis: current status of the problem
by: N. V. Chichasova, et al.
Published: (2024-12-01)

First available biosimilar monoclonal antibodies
by: Zh. I. Avdeeva, et al.
Published: (2018-02-01)

Pharmacist intervention through protocol-based pharmacotherapy management is effective to ensure safety in invasive procedures for chronic liver disease
by: Yuuka Shibata, et al.
Published: (2025-08-01)

Adaptation of the REINVENT neural network architecture to generate potential HIV-1 entry inhibitors
by: D. A. Varabyeu, et al.
Published: (2024-09-01)

Development of a generative adversarial neural network for identification of potential HIV-1 inhibitors by deep learning methods
by: G. I. Nikolaev, et al.
Published: (2020-03-01)

Three ways of organising general practitioner’s medical services in sheltered housing. A qualitative study
by: Laila Tingvold, et al.
Published: (2023-10-01)

Experimental Validation of an <i>In Vitro</i> Method for Assessing Insulin-Dependent Glucose Uptake
by: A. N. Afanasyeva, et al.
Published: (2023-03-01)

Natural killer cell granule protein 7 contributes to CD8+ T cell-mediated platelet apoptosis in immune thrombocytopenia
by: Xiaolin Wang, et al.
Published: (2025-07-01)

Biosimilars - drugs of the future
by: E. A. Eltcova, et al.
Published: (2014-04-01)

The role of sTNFSF14 in the liver mitochondrial dynamics in obese patients
by: A. A. Komar, et al.
Published: (2021-10-01)

Repurposing the selective estrogen receptor modulator bazedoxifene to suppress gastrointestinal cancer growth
by: Pathum Thilakasiri, et al.
Published: (2019-03-01)