Intracellular pathogen effector reprograms host gene expression by inhibiting mRNA decay
Abstract Legionella pneumophila, an intracellular bacterial pathogen, injects effector proteins into host cells to manipulate cellular processes and promote its survival and proliferation. Here, we reveal a unique mechanism by which the Legionella effector PieF perturbs host mRNA decay by targeting...
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| Main Authors: | Yevgen Levdansky, Justin C. Deme, David J. Turner, Claire T. Piczak, Filip Pekovic, Anna L. Valkov, Sergey G. Tarasov, Susan M. Lea, Eugene Valkov |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-025-61194-2 |
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